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HomeProduct name listLACTAMIDE

LACTAMIDE

Synonym(s):DL-Lactic acid amide

  • CAS NO.:2043-43-8
  • Empirical Formula: C3H7NO2
  • Molecular Weight: 89.09
  • MDL number: MFCD00008017
  • EINECS: 218-049-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-11-15 13:42:31
LACTAMIDE Structural

What is LACTAMIDE?

The Uses of LACTAMIDE

Lactamide is used as a synthetic raw material in organic chemistry, as an additive in cosmetics, and as a preservative in frozen semen and fertilized eggs in livestock reproduction studies.

Definition

ChEBI:Lactamide is a monocarboxylic acid amide that is lactic acid in which the carboxylic acid group has been converted to the corresponding carboxamide. It is a monocarboxylic acid amide and a secondary alcohol. It is functionally related to a rac-lactic acid.

Synthesis

α-Hydroxy methyl ester (10 mmol, 1.0 equiv) was added into the 100 ml RBF, anda saturated methanol solution of ammonia (20 ml, 38 equiv) was added underthe ice-water bath and stirred overnight. The mixture was concentrated underreduced pressure and in most case Lactamide were obtained in high yields,while in rare occasions purified by flash chromatography.

2043-43-8.png

Properties of LACTAMIDE

Melting point: 73-76 °C(lit.)
Boiling point: 165.17°C (rough estimate)
Density  1.1948 (rough estimate)
refractive index  1.4368 (estimate)
pka 13.34±0.20(Predicted)
form  powder to crystal
color  White to Almost white
Water Solubility  782.20g/L(25 ºC)
CAS DataBase Reference 2043-43-8(CAS DataBase Reference)

Safety information for LACTAMIDE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P312:Call a POISON CENTER or doctor/physician if you feel unwell.
P362:Take off contaminated clothing and wash before reuse.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313:IF SKIN irritation occurs: Get medical advice/attention.
P337+P313:IF eye irritation persists: Get medical advice/attention.
P405:Store locked up.
P403+P233:Store in a well-ventilated place. Keep container tightly closed.
P501:Dispose of contents/container to..…

Computed Descriptors for LACTAMIDE

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