L-Histidine hydrochloride
Synonym(s):L -Histidine monohydrochloride solution
- CAS NO.:1007-42-7
- Empirical Formula: C6H10ClN3O2
- Molecular Weight: 191.62
- MDL number: MFCD00066569
- EINECS: 213-754-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-05 19:05:58
What is L-Histidine hydrochloride?
Purification Methods
The dihydrochloride crystallises from water or aqueous EtOH and is washed with acetone, then diethyl ether. Alternatively convert it to the histidine di-(3,4-dichlorobenzenesulfonate) salt by dissolving 3,4-dichlorobenzenesulfonic acid (1.5g/10mL) in the aqueous histidine solution with warming, and then the solution is cooled in ice. The resulting crystals (m 280o dec) can be recrystallised from 5% aqueous 3,4-dichlorobenzenesulfonic acid, then dried over CaCl2 under vacuum, and washed with diethyl ether to remove Purification of Biochemicals — Amino Acids and Peptides excess reagent. The dihydrochloride can be regenerated by passing the solution through a Dowex-1 (Cl-form) ion-exchange column. The solid is obtained by evaporation of the solution on a steam bath or better in a vacuum. [Greenstein & Winitz, The Amino Acids Vol 3 p 1976 1961, Beilstein 25/16 V 366.]
Properties of L-Histidine hydrochloride
Melting point: | 240-245 °C (dec.) |
alpha | [α]D20 +7.0~+10.0°(c=2,HCl) |
storage temp. | Inert atmosphere,Room Temperature |
CAS DataBase Reference | 1007-42-7(CAS DataBase Reference) |
Safety information for L-Histidine hydrochloride
Computed Descriptors for L-Histidine hydrochloride
New Products
ALUMINIUM IODIDE 100 GM BUFFER CAPSULE PH 7.0 - 10 CAP BUFFER SOLUTION PH 9.5 (BORATE) EZEE BLUE GEL STAINER BORAX CARMINE (GRENACHERS ALCOHOLIC) POTASSIUM IODATE - IODIDE SOLN 0.1 N Dabigatran Acyl-O3-D-Glucuronide Trifluoroacetic Acid Salt Isofolic Acid Dabigatran 2-O-acylglucuronide metabolite Dabigatran Acyl-?-D- glucuronide Trifluroacetic Acid Erythromycin EP Impurity A Desloratidine Related Compound ARelated products of tetrahydrofuran
You may like
-
L-Histidine hydrochloride 95% CAS 1007-42-7View Details
1007-42-7 -
Dechloro DesloratadineView Details
-
Dehydro DesloratadineView Details
-
Edoxaban Impurity 57View Details
2089454-69-1 -
Eltrombopag N-Oxide ImpurityView Details
2734533-17-4 -
Empagliflozin Bromo ImpurityView Details
-
Glycopyrronium Bromide EP Impurity IView Details
1404617-94-2 -
Ipratropium EP Impurity BView Details
58073-59-9