L(+)-Asparagine monohydrate
Synonym(s):L-Asparagine monohydrate;Asparagine Monohydrate;Asparaginic acid semiamide, Asn;(S)-(+)-2-Aminosuccinamic acid;(S)-2-Aminosuccinic acid 4-amide
- CAS NO.：5794-13-8
- Empirical Formula: C4H10N2O4
- Molecular Weight: 150.13
- MDL number: MFCD00151038
- EINECS: 611-593-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-21 22:41:43
What is L(+)-Asparagine monohydrate?
Chemical properties
White or almost white, crystalline powder or colourless crystals.
The Uses of L(+)-Asparagine monohydrate
L-Asparagine is a naturally occurring amino acid that is not an essential for humans and can be synthesized from central metabolic pathway intermediates.
The Uses of L(+)-Asparagine monohydrate
L-Asparagine is a naturally occurring proteinogenic amino acid, used in biomanufacturing cell culture systems for the production of therapeutic recombinant proteins and monoclonal antibodies. It is used in the biosynthesis of proteins. It is also required for development and function of the brain.
General Description
Asparagine biosynthesis is catalyzed by glutamine-dependent asparagine synthetase in mammalian tissues. Elevated levels of free asparagine is observed in plants facing stress in the form of drought or high salt. It is also present in senescing leaves and germinating seeds.
Biochem/physiol Actions
Asparagine has high nitrogen to carbon ratio and is a key regulator for nitrogen storage and transport. Its thermal degradation in the presence of sugars leads to the acrylamide formation in foods. Asparagine serves as an amino acid exchange factor and is essential for amino acid homeostasis. It favors cancer cell proliferation.
Properties of L(+)-Asparagine monohydrate
| Melting point: | 233-235 °C(lit.) |
| Boiling point: | 271.66°C (rough estimate) |
| alpha | 35 º (c=10, 6N HCl) |
| Density | 1,543 g/cm3 |
| refractive index | 31 ° (C=10, HCl) |
| storage temp. | 2-8°C |
| solubility | H2O: 20 mg/mL |
| form | powder |
| color | White to Off-white |
| PH | 4.0-5.5 (20g/l, H2O, 20℃) |
| Odor | at 100.00?%. odorless |
| Water Solubility | 30 g/L (20 ºC) |
| Merck | 14,837 |
| BRN | 5767869 |
| CAS DataBase Reference | 5794-13-8(CAS DataBase Reference) |
Safety information for L(+)-Asparagine monohydrate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for L(+)-Asparagine monohydrate
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