L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROYL

Synonym(s):L-α-Lysophosphatidylcholine, stearoyl;1-octadecanoyl-sn-glycero-3-phosphocholine; PC(18:0/0:0);Lysolecithin, stearoyl

CAS NO.：19420-57-6
Empirical Formula: C26H54NO7P
Molecular Weight: 523.68
MDL number: MFCD00050427
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-19 23:02:33

L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROYL Structural

What is L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROYL?

Description

Lyso-PC (18:0), also known as 1-stearoyl-sn-glycero-3-phosphocholine, is a lysophosphocoline connceted to hydrophobic fatty acid tail (stearic acid) by a glycerol.

The Uses of L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROYL

Stearoyl L-α-Lysolecithin is an bioactive lysophosphatidylcholine derived compound found to be released by bronchial epithelial cells. Stearoyl L-α-Lysolecithin have also been utilized in the development of liposomes and michelles by drug transdermal delivery devices.

The Uses of L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROYL

18:0 Lyso PC has been used:

to functionalize carbon nanotubes (CNTs) for the development of methods to attach DNA to CNTs
to increase the level of lysophosphatidic acid (LPA) in mouse
to induce TNF receptor associated factor 3 interacting protein 2 (TRAF3IP2) expression in endothelial cells (EC)

What are the applications of Application

1-Stearoyl-sn-glycero-3-phosphocholine is a chemical used in lipid metabolism studies

Definition

ChEBI: 1-stearoyl-sn-glycero-3-phosphocholine is a lysophosphatidylcholine 18:0 in which the acyl substituent is located at position 1 and is specified as stearoyl. It has a role as a mouse metabolite and an apoptosis inducer. It is a 1-O-acyl-sn-glycero-3-phosphocholine and a lysophosphatidylcholine 18:0. It is functionally related to an octadecanoic acid.

Biochem/physiol Actions

1-Stearoyl-sn-glycero-3-phosphocholine (LPC, Lyso-PC) is used in the development of drug transdermal delivery devices such as liposomes and micelles.

Properties of L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROYL

Melting point:	100-200 °C
storage temp.	-20°C
solubility	Methanol (Slightly, Heated, Sonicated), Water (Slightly, Heated)
form	powder
color	white
Stability:	Hygroscopic, Moisture Sensitive

Safety information for L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROYL

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H331:Acute toxicity,inhalation H336:Specific target organ toxicity,single exposure; Narcotic effects H351:Carcinogenicity H372:Specific target organ toxicity, repeated exposure H412:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P201:Obtain special instructions before use. P273:Avoid release to the environment. P302+P352:IF ON SKIN: wash with plenty of soap and water. P308+P313:IF exposed or concerned: Get medical advice/attention.