L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROYL
Synonym(s):L -α-Lysophosphatidylcholine, stearoyl;1-octadecanoyl-sn-glycero-3-phosphocholine; PC(18:0/0:0);Lysolecithin, stearoyl
- CAS NO.：19420-57-6
- Empirical Formula: C26H54NO7P
- Molecular Weight: 523.68
- MDL number: MFCD00050427
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-04-07 18:44:46
What is L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROYL?
Description
Lyso-PC (18:0), also known as 1-stearoyl-sn-glycero-3-phosphocholine, is a lysophosphocoline connceted to hydrophobic fatty acid tail (stearic acid) by a glycerol.
The Uses of L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROYL
Stearoyl L-α-Lysolecithin is an bioactive lysophosphatidylcholine derived compound found to be released by bronchial epithelial cells. Stearoyl L-α-Lysolecithin have also been utilized in the development of liposomes and michelles by drug transdermal delivery devices.
The Uses of L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROYL
18:0 Lyso PC has been used:
- to functionalize carbon nanotubes (CNTs) for the development of methods to attach DNA to CNTs
- to increase the level of lysophosphatidic acid (LPA) in mouse
- to induce TNF receptor associated factor 3 interacting protein 2 (TRAF3IP2) expression in endothelial cells (EC)
What are the applications of Application
1-Stearoyl-sn-glycero-3-phosphocholine is a chemical used in lipid metabolism studies
Definition
ChEBI: 1-stearoyl-sn-glycero-3-phosphocholine is a lysophosphatidylcholine 18:0 in which the acyl substituent is located at position 1 and is specified as stearoyl. It has a role as a mouse metabolite and an apoptosis inducer. It is a 1-O-acyl-sn-glycero-3-phosphocholine and a lysophosphatidylcholine 18:0. It is functionally related to an octadecanoic acid.
Biochem/physiol Actions
1-Stearoyl-sn-glycero-3-phosphocholine (LPC, Lyso-PC) is used in the development of drug transdermal delivery devices such as liposomes and micelles.
Properties of L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROYL
| Melting point: | 100-200 °C |
| storage temp. | -20°C |
| solubility | Methanol (Slightly, Heated, Sonicated), Water (Slightly, Heated) |
| form | powder |
| color | white |
| Stability: | Hygroscopic, Moisture Sensitive |
Safety information for L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROYL
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H331:Acute toxicity,inhalation H336:Specific target organ toxicity,single exposure; Narcotic effects H351:Carcinogenicity H372:Specific target organ toxicity, repeated exposure H412:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P273:Avoid release to the environment. P302+P352:IF ON SKIN: wash with plenty of soap and water. P308+P313:IF exposed or concerned: Get medical advice/attention. |
Computed Descriptors for L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROYL
| InChIKey | IHNKQIMGVNPMTC-RUZDIDTESA-N |
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