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HomeProduct name listL-ABRINE

L-ABRINE

Synonym(s):Nα-Methyl-L-tryptophan;L-Abrine

  • CAS NO.:526-31-8
  • Empirical Formula: C12H14N2O2
  • Molecular Weight: 218.25
  • MDL number: MFCD00005645
  • EINECS: 208-388-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-20 11:41:24
L-ABRINE Structural

What is L-ABRINE?

Chemical properties

white to light grey crystalline powder or crystals

The Uses of L-ABRINE

L-Abrine is an indoleamino acid that displays radical scavenging and antioxidant properties.

Definition

ChEBI: A N-methyl-L-alpha-amino acid that is the Nalpha-methyl derivative of L-tryptophan.

Biochem/physiol Actions

An indoleamino acid that shows radical scavenging and antioxidant properties in vitro.

Purification Methods

Crystallise L-abrine from H2O or EtOH/H2O mixture and dry it for 2days at 60o in high vacuum; it has m 275-290o(dec with browning at 230o) and [] D +47.2o (c 2, 0.5N HCl) [Peter et al. Helv Chim Acta 46 577 1963]. [Gregory & Morley J Chem Soc 913 1968, Beilstein 22/14 V 40.]

Properties of L-ABRINE

Melting point: >300 °C (dec.)(lit.)
Boiling point: 358.94°C (rough estimate)
alpha  D21 +44° (0.28 g in 10 ml 0.5N HCl)
Density  1.272±0.06 g/cm3 (20 ºC 760 Torr)
refractive index  65 ° (C=1, 0.5mol/L NaOH)
storage temp.  under inert gas (nitrogen or Argon) at 2–8 °C
solubility  H2O : 2 mg/mL (9.16 mM; ultrasonic and adjust pH to 10 with NaOH)
form  Cryst.
pka 2.32±0.10(Predicted)
color  Off-white to light yellow
optical activity [α]20/D +65°, c = 1 in 0.5 M NaOH
Merck  14,10
BRN  86638
CAS DataBase Reference 526-31-8(CAS DataBase Reference)

Safety information for L-ABRINE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

Computed Descriptors for L-ABRINE

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