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HomeProduct name listIRL-1620

IRL-1620

IRL-1620 Structural

What is IRL-1620?

Biological Activity

IRL-1620 is a potent and selective endorphin receptor (endothelin receptor) type B agonist with a Ki of 16 pM.

in vitro

IRL-1620 is the most potent and specific ligand for the ETB receptor (K i ETA/ K i ETB=120,000) as judged by the K i values for ETA (19 μM) and ETB (16 PM) receptors. IRL-1620 is 60 times more selective for the ETB receptor than ET-3 (K i ETA /K i ETB=1,900).

storage

-20°C (desiccate)

Properties of IRL-1620

Boiling point: 2096.6±65.0 °C(Predicted)
Density  1.347±0.06 g/cm3(Predicted)
storage temp.  −20°C
solubility  Soluble in DMSO
form  powder
pka 3.39±0.10(Predicted)
color  white
Water Solubility  Soluble in water (0.5 mg/ml)

Safety information for IRL-1620

Computed Descriptors for IRL-1620

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