IRL-1620
- CAS NO.:142569-99-1
- Empirical Formula: C86H117N17O27
- Molecular Weight: 1820.95
- MDL number: MFCD00214284
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-02 21:09:47
What is IRL-1620?
Biological Activity
IRL-1620 is a potent and selective endorphin receptor (endothelin receptor) type B agonist with a Ki of 16 pM.
in vitro
IRL-1620 is the most potent and specific ligand for the ETB receptor (K i ETA/ K i ETB=120,000) as judged by the K i values for ETA (19 μM) and ETB (16 PM) receptors. IRL-1620 is 60 times more selective for the ETB receptor than ET-3 (K i ETA /K i ETB=1,900).
storage
-20°C (desiccate)
Properties of IRL-1620
Boiling point: | 2096.6±65.0 °C(Predicted) |
Density | 1.347±0.06 g/cm3(Predicted) |
storage temp. | −20°C |
solubility | Soluble in DMSO |
form | powder |
pka | 3.39±0.10(Predicted) |
color | white |
Water Solubility | Soluble in water (0.5 mg/ml) |
Safety information for IRL-1620
Computed Descriptors for IRL-1620
New Products
Tert-butyl bis(2-chloroethyl)carbamate (S)-3-Aminobutanenitrile hydrochloride N-Boc-D-alaninol N-BOC-D/L-ALANINOL N-octanoyl benzotriazole 4-Hydrazinobenzoic acid 3,4-Dibenzyloxybenzaldehyde Electrolytic Iron Powder 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 4-HYDROXY BENZYL ALCOHOL 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) S-2-CHLORO PROPIONIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 3-(Hydroxymethyl)benzoate N-Boc-2-chloroethylamine 1-Bromo-2-methoxy-3-nitrobenzene N-Methyl-3-cyclopenten-1-amine 2-Bromo-3-hydroxybenzaldehyde 1H-indazole-5-carboxamideRelated products of tetrahydrofuran
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