Hexapeptide-11
- CAS NO.：161258-30-6
- Empirical Formula: C36H48N6O7
- Molecular Weight: 676.8
- EINECS: 000-000-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-06-11 18:14:38
What is Hexapeptide-11?
Description
Hexapeptide-11 is a novel modulator of the proteostasis network in human diploid fibroblasts.
The Uses of Hexapeptide-11
Hexapeptide-11 reduces the appearance of fine lines and wrinkles, making this an excellent addition to all kinds of skin care and anti-aging products. It has a unique set of amino acids that help to manipulate collagen levels and boost elasticity in the skin.
Benefits
Hexapeptide-11 promote the fibroblast to produce collagen and elastin,enhance skin elasticity and firmness, fadeout the fine wrinkle.Its recommended dosage is 0.5~3%.
Physiological effects
Exposure of fibroblasts to Hexapeptide-11 promoted dose and time-dependent activation of proteasome, autophagy, chaperones and antioxidant responses related genes. Moreover, it promoted increased nuclear accumulation of Nrf2; higher expression levels of proteasomal protein subunits and increased proteasome peptidase activities. In line with these findings we noted that Hexapeptide-11 conferred significant protection in fibroblasts against oxidative-stress-mediated premature cellular senescence, while at in vivo skin deformation assays in human subjects it improved skin elasticity.
Properties of Hexapeptide-11
| Boiling point: | 1035.1±65.0 °C(Predicted) |
| Density | 1.269±0.06 g/cm3(Predicted) |
| pka | 3.43±0.20(Predicted) |
Safety information for Hexapeptide-11
Computed Descriptors for Hexapeptide-11
| InChIKey | GFEYWOGCSROPRT-OBXVVNIGSA-N |
| SMILES | C(O)(=O)[C@@H]1CCCN1C(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC1=CC=CC=C1)N |
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