inulicin
- CAS NO.：33627-41-7
- Empirical Formula: C17H24O5
- Molecular Weight: 308.37
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:54:56
What is inulicin?
Biological Activity
Inulicin (1-O-Acetylbritannilactone) is an active compound isolated from Inula Britannica L. It inhibits VEGF-mediated activation of Src and FAK. It also inhibits LPS-induced PGE2 production and COX-2 expression, as well as NF-κB activation and translocation.
in vivo
Administration of a single dose of Inulicin (1-O-Acetylbritannilactone; 12 mg/kg/day) remarkably suppresses growth of A549 xenografts in nude mice. In vivo microvessels formation and Src activation are also significantly inhibited in Inulicin-treated xenograft tumors. To investigate the potential activity of Inulicin in vivo, a nude mice xenograft model is applied.
Properties of inulicin
| Melting point: | 124.0-126.1 °C |
| Boiling point: | 481.7±45.0 °C(Predicted) |
| Density | 1.16 |
| storage temp. | 4°C, protect from light |
| solubility | DMSO: soluble |
| form | A solid |
| pka | 13.71±0.60(Predicted) |
| color | White to off-white |
Safety information for inulicin
Computed Descriptors for inulicin
New Products
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