1-BOC-INDOLINE
Synonym(s):N-(tert-Butoxycarbonyl)-2,3-dihydroindole
- CAS NO.：143262-10-6
- Empirical Formula: C13H17NO2
- Molecular Weight: 219.28
- MDL number: MFCD01318399
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is 1-BOC-INDOLINE?
The Uses of 1-BOC-INDOLINE
Reactant in preparation of aryl alkyl amines via alkylation reactions catalyzed by Pd 1 Reactant in preparation of allyl- and arylindolines 2 Reactant in modular indole synthesis of the highly strained CDEF parent tetracycle of nodulisporic acids A and B 3 Reactant in asymmetric synthesis of β-amino esters via rhodium prolinate complex-catalyzed α-C-H activation / carbenoid insertion reactions 4 Reactant in preparation of substituted indolines and tetrahydroquinolines via cycloaddition approach.
The Uses of 1-BOC-INDOLINE
- Reactant in preparation of aryl alkyl amines via alkylation reactions catalyzed by Pd
- Reactant in preparation of allyl- and arylindolines
- Reactant in modular indole synthesis of the highly strained CDEF parent tetracycle of nodulisporic acids A and B
- Reactant in asymmetric synthesis of β-amino esters via rhodium prolinate complex-catalyzed α-C-H activation / carbenoid insertion reactions
- Reactant in preparation of substituted indolines and tetrahydroquinolines via cycloaddition approach
General Description
tert -Butyl indoline-1-carboxylate is an N-substituted indoline derivative.
Properties of 1-BOC-INDOLINE
| Melting point: | 46-50 °C(lit.) |
| Boiling point: | 83-84 °C0.1 mm Hg(lit.) |
| Density | 1.114±0.06 g/cm3(Predicted) |
| Flash point: | >230 °F |
| pka | 0.84±0.20(Predicted) |
| BRN | 5336249 |
| CAS DataBase Reference | 143262-10-6 |
Safety information for 1-BOC-INDOLINE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1-BOC-INDOLINE
New Products
4,4-Difluoropiperidine hydrochloride tert-butyl 9-methoxy-3-azaspiro[5.5]undecane-3-carboxylate Indole Methyl Resin N-Isopropylurea N,N-Dicyclohexylcarbodiimide(DCC) MELDRUMS ACID 5-METHYLISOXAZOLE-4-CARBOXYLIC ACID Magnessium Bis glycinate Zinc ascorbate 1-bromo-2-butyne 2-acetamidophenol 9(10H)-anthracenone Erythrosin B, 4-Piperidinopiperidine 2-((4-morpholinophenylamino) (methylthio) methylene) malononitrile 2,4-dihydroxybenzaldehyde 3-(4-morpholinophenylamino)-5-amino-1H-pyrazole-4-carbonitrile Methyl 2-methylquinoline-6-carboxylate 2,6-dichloro-4-nitropyridine 4-Bromo-2-chlorobenzonitrile 2-(benzylamino)acetic acid hydrochloride 4-(tert-Butoxycarbonylamino)but- 2-ynoic acid 3,4-dihydro-2H-benzo[b][1,4]dioxepine 1-Phenyl-1-cycloprppanecarboxylicacidRelated products of tetrahydrofuran
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