1-BOC-INDOLINE

Synonym(s):N-(tert-Butoxycarbonyl)-2,3-dihydroindole

CAS NO.：143262-10-6
Empirical Formula: C13H17NO2
Molecular Weight: 219.28
MDL number: MFCD01318399
SAFETY DATA SHEET (SDS)
Update Date: 2023-07-14 17:31:15

What is 1-BOC-INDOLINE?

The Uses of 1-BOC-INDOLINE

Reactant in preparation of aryl alkyl amines via alkylation reactions catalyzed by Pd 1 Reactant in preparation of allyl- and arylindolines 2 Reactant in modular indole synthesis of the highly strained CDEF parent tetracycle of nodulisporic acids A and B 3 Reactant in asymmetric synthesis of β-amino esters via rhodium prolinate complex-catalyzed α-C-H activation / carbenoid insertion reactions 4 Reactant in preparation of substituted indolines and tetrahydroquinolines via cycloaddition approach.

The Uses of 1-BOC-INDOLINE

Reactant in preparation of aryl alkyl amines via alkylation reactions catalyzed by Pd
Reactant in preparation of allyl- and arylindolines
Reactant in modular indole synthesis of the highly strained CDEF parent tetracycle of nodulisporic acids A and B
Reactant in asymmetric synthesis of β-amino esters via rhodium prolinate complex-catalyzed α-C-H activation / carbenoid insertion reactions
Reactant in preparation of substituted indolines and tetrahydroquinolines via cycloaddition approach

General Description

tert -Butyl indoline-1-carboxylate is an N-substituted indoline derivative.

Properties of 1-BOC-INDOLINE

Melting point:	46-50 °C(lit.)
Boiling point:	83-84 °C0.1 mm Hg(lit.)
Density	1.114±0.06 g/cm3(Predicted)
Flash point:	>230 °F
pka	0.84±0.20(Predicted)
BRN	5336249
CAS DataBase Reference	143262-10-6

Safety information for 1-BOC-INDOLINE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.