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HomeProduct name listilludin M

illudin M

illudin M Structural

What is illudin M?

Description

Illudin M is a cytotoxic sesquiterpene from the fungus O. illudens that alkylates DNA. It is cytotoxic to HL-60 human leukemia cells at 6-100 nM. Illudin M was used as a base structure for the development of potential anticancer agents with less toxicity and improved efficacy. It is closely related to illudin S , which has been the focus of additional studies.

The Uses of illudin M

Illudin M is a cytotoxic sesquiterpene from Omphalotus illudens and Granulobasidium vellereum. It acts as an alkylating agent that can cause inhibition of cell growth or replication.

Definition

ChEBI: Illudin M is a sesquiterpenoid.

Properties of illudin M

Melting point: 120-122.5° (Matsumoto); mp 128-130° (McMorris)
Boiling point: 452.4±45.0 °C(Predicted)
Density  1.24±0.1 g/cm3(Predicted)
storage temp.  Store at -20°C
solubility  DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form  A solid
pka 12.57±0.70(Predicted)
color  Off-white to light yellow

Safety information for illudin M

Computed Descriptors for illudin M

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