ILIMAQUINONE
Synonym(s):3-[(Decahydro-1β,2β,4aβ-trimethyl-5-methylene-1-napthyl)methyl]-2-hydroxy-5-methoxybenzoquinone, IQ;Ilimaquinone - CAS 71678-03-0 - Calbiochem
- CAS NO.:71678-03-0
- Empirical Formula: C22H30O4
- Molecular Weight: 358.47
- MDL number: MFCD22200891
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:11
What is ILIMAQUINONE?
Description
Ilimaquinone is a natural sesquiterpene quinone that has antimicrobial, anti-
The Uses of ILIMAQUINONE
Ilimaquinone is an ADP-ribosylation factor (ARF) and β-COP to the Golgi membrane inhibitor.
The Uses of ILIMAQUINONE
Biological probe for intracellular communications and vesicle-mediated transport.
What are the applications of Application
Ilimaquinone is an ADP-ribosylation factor (ARF) and β-COP to the Golgi membrane inhibitor
Definition
ChEBI: A natural product found in Dactylospongia elegans.
General Description
A cell-permeable marine sponge metabolite with anti-microbial, anti-HIV, anti-inflammatory, and anti-mitotic properties. Induces a complete and reversible breakdown of Golgi membranes into smaller vesicular structures and causes depolymerization of microtubules. Inhibits cellular methylations through its interaction with S-adenosylhomocysteinase. Blocks the cytotoxicity of ricin and diphtheria toxin. Acts as an inhibitor of the RNase H activity of HIV-1.
Biochem/physiol Actions
Primary TargetInduces a complete and reversible breakdown of Golgi membranes into smaller vesicular structures and causes depolymerization of microtubules.
Properties of ILIMAQUINONE
Melting point: | 108-110℃ (pentane ) |
Boiling point: | 478.4±45.0 °C(Predicted) |
alpha | D23 -23.2° (c = 1.12 in CHCl3) |
Density | 1.14±0.1 g/cm3(Predicted) |
storage temp. | −20°C |
solubility | DMSO: Soluble; Ethanol: Soluble; Hexane: Soluble; Methanol: Soluble |
pka | 2.92±0.50(Predicted) |
form | Red solid |
color | Light yellow to brown |
Safety information for ILIMAQUINONE
Computed Descriptors for ILIMAQUINONE
New Products
6-Bromo 2-Iodo Indole Pyridine 2,4,6-Tricarboxaldehyde Fosfomycin EP impurity D Ivermectin EP Impurity B Rimegepant Impurity 3 Tubulysin M Tubulysin G Tubulysin C Tubulysin E Potassium HMDS (1.0 M in THF) 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Imeglimin Hydrochloride IH 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Calcium Sodium Phosphosilicate IH 2-(4-Bromopyridin-2-yl)acetonitrile Methyl 4-amino-3-(piperidin-1-yl)benzoate 5-Aminophthalazine Benzene butanoic acid, 2-hydroxy-3-iodo-, methyl ester Methyl 4-amino-3-(pyrrolidin-1-yl)benzoate 3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione 3-HYDROXY-8-FLUORONAPHTHALENE-1-BORONIC ACID PINACOL ESTER ((E)-3-(Dimethylamino)-2-methylacrylaldehydeRelated products of tetrahydrofuran
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