HYDROQUINIDINE
Synonym(s):(9S)-10,11-Dihydro-6′-methoxycinchonan-9-ol;Dihydroquinidine;Hydroquinidine
- CAS NO.:1435-55-8
- Empirical Formula: C20H26N2O2
- Molecular Weight: 326.43
- MDL number: MFCD00135599
- EINECS: 215-862-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:17
What is HYDROQUINIDINE?
Chemical properties
Solid
The Uses of HYDROQUINIDINE
antiarrhythmic, antimalarial
What are the applications of Application
A useful biochemical for proteomics research
Purification Methods
It is slightly soluble in Et2O and H2O but readily soluble in hot EtOH. [Heidelberger & Jacobs J Am Chem Soc 41 826 1919, King J Chem Soc 523 1946.] The hydrochloride has m 273-274o, [] 26D +184o (c 1.3, MeOH) and is very soluble in MeOH and CHCl3, but less soluble in H2O, EtOH and still less soluble in dry Me2CO. [Kyker & Lewis J Biol Chem 157 707 1945, Emde Helv Chim Acta 15 557 1932, Beilstein 23/13 V 340.]
Properties of HYDROQUINIDINE
Melting point: | 169-170 °C(lit.) |
Boiling point: | 464.47°C (rough estimate) |
alpha | 226 º (C=2 IN ETOH) |
Density | 1.1117 (rough estimate) |
refractive index | 1.6800 (estimate) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | chloroform: 0.1 g/mL, clear |
pka | 12.80±0.20(Predicted) |
form | A crystalline solid |
color | White to off-white |
optical activity | [α]25/D +226°, c = 2 in ethanol |
Merck | 13,4831 |
BRN | 91441 |
CAS DataBase Reference | 1435-55-8(CAS DataBase Reference) |
NIST Chemistry Reference | Hydroquinidine(1435-55-8) |
Safety information for HYDROQUINIDINE
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P501:Dispose of contents/container to..… |
Computed Descriptors for HYDROQUINIDINE
InChIKey | LJOQGZACKSYWCH-LHFMAAMQSA-N |
New Products
4-Fluorophenylacetic acid 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate (6-METHYL-[1,3]DITHIOLO[4,5-b]QUINOXALIN-2-ONE INDAZOLE-3-CARBOXYLIC ACID 4-IODO BENZOIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5,6-Dimethoxyindanone 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 2-aminopropyl benzoate hydrochloride 1-(4-(aminomethyl)benzyl)urea hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
hydroquinidine,monohydrochlorid
4-HEPTYLPYRIDINE
(R)-(+)-1-(4-PYRIDYL)ETHANOL
HYDROQUINIDINE
(2R,4S,5R)-2-Hydroxymethyl-5-ethylquinuclidine
HYDROQUINIDINE 2,5-DIPHENYL-4,6-PYRIMIDINEDIYL DIETHER
HYDROQUINIDINE 1,4-PHTHALAZINEDIYL DIETHER
HYDROCINCHONINE
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