HEPTAMETHYLDISILAZANE

CAS NO.：134340-00-4
Empirical Formula: C7H21NSi2
Molecular Weight: 175.42
MDL number: MFCD00008262
EINECS: 678-035-1
SAFETY DATA SHEET (SDS)
Update Date: 2023-06-08 17:06:38

What is HEPTAMETHYLDISILAZANE?

Physical properties

colorless liquid, bp 70°Cat 25 mm Hg; its hydrochloride salt, mp 191 °C.

The Uses of HEPTAMETHYLDISILAZANE

Methanamine, 1,1-Bis(trimethylsilyl) is reagent used for the preparation of N-bis(trimethylsilyl)methyl amines, imines, as a synthetic equivalent of N-methyl, N- (trimethylsilyl)methyl carbanion, and [N-CH] dianion synthons, as an N-protecting group.

Preparation

It is prepared by lithium metal mediated reductive silylation of trimethylsilyl cyanide.

Properties of HEPTAMETHYLDISILAZANE

Boiling point:	144-147 °C(lit.)
Density	0.799 g/mL at 20 °C(lit.)
refractive index	n20/D 1.421(lit.)
solubility	sol ether, alcohol, dichloromethane, and most organic solvents; hydrochloride salt sol in H2O, alcohol, DMF, DMSO.
pka	11.57±0.29(Predicted)
form	clear liquid
color	Colorless to Almost colorless

Safety information for HEPTAMETHYLDISILAZANE

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Corrosion Corrosives GHS05
GHS Hazard Statements	H226:Flammable liquids H314:Skin corrosion/irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P370+P378:In case of fire: Use … for extinction. P405:Store locked up. P403+P235:Store in a well-ventilated place. Keep cool. P501:Dispose of contents/container to..…