HEMOCYANIN, KEYHOLE LIMPET
Synonym(s):KLH;Keyhole limpet hemocyanin;Blue Carrier;Hemocyanin, Keyhole Limpet, Megathura crenulata;Hemocyanin, Keyhole Limpet, Megathura crenulata, BES/Mg2+ Buffer
- CAS NO.:9013-72-3
- Molecular Weight: 0
- MDL number: MFCD00131280
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:03
What is HEMOCYANIN, KEYHOLE LIMPET?
The Uses of HEMOCYANIN, KEYHOLE LIMPET
Hemocyanin from Limulus polyphemus hemolymph has been used:
- in electrophoretic field gradient focusing as a reference standard for optimizing fluorescence quenching for noncolored proteins
- as standard protein for pH based crystallization screening experiments
- in peptide conjugation studies
The Uses of HEMOCYANIN, KEYHOLE LIMPET
Keyhole limpet hemocyanin (KLH) is a strong and well known immune-stimulant in both experimental animals and humans. It has been used as a hapten carrier protein to enhance antigen-specific T cell priming and is known to stimulate a CD4+ T-cell response.
Hemocyanin was used to study if antipeptide antibodies specifically recognize the l1 protein of the human papilloma virus of type 31. It was also used to study the acid-induced unfolding of didecameric keyhole limpet hemocyanin.
General Description
Gastropod hemocyanins are massive glycoproteins (4 to 8 MDa) designed by an intricate arrangement of 10 subunits that are self-assembled into hollow cylinders 35 nm in diameter.
Biochem/physiol Actions
The largest hemocyanin molecules consisting of 48 (8 × 6) subunits are present in horseshoe crabs (Limulus polyphemus) have up to eight distinct subunits type (6 × subunit type I, 8 × II, 2 × IIA, 8 × IIIA, 8 × IIIB, 8 × IV, 4 × V, 4 × VI).
Properties of HEMOCYANIN, KEYHOLE LIMPET
storage temp. | 2-8°C |
solubility | H2O: soluble |
form | PBS solution |
color | Off-white to gray |
Safety information for HEMOCYANIN, KEYHOLE LIMPET
Computed Descriptors for HEMOCYANIN, KEYHOLE LIMPET
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
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