H2N-PEG8-tBu
- CAS NO.:756526-06-4
- Empirical Formula: C23H47NO10
- Molecular Weight: 497.62
- MDL number: MFCD11041142
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-21 16:41:51
What is H2N-PEG8-tBu?
Description
Amino-PEG8-t-butyl ester is a monodisperse PEG linker containing an amino group with a t-butyl protected carboxyl group.The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
The Uses of H2N-PEG8-tBu
H2N-PEG8-tBu is a cleavable 8-unit PEG-ADC linker for antibody drug conjugate (ADC) synthesis.
Properties of H2N-PEG8-tBu
Boiling point: | 544.3±45.0 °C(Predicted) |
Density | 1.067±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C(protect from light) |
solubility | Soluble in Water, DMSO, DCM, DMF |
pka | 8.74±0.10(Predicted) |
color | Colorless to light yellow |
Safety information for H2N-PEG8-tBu
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for H2N-PEG8-tBu
New Products
(S)-3-Aminobutanenitrile hydrochloride 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid 1-Bromo-3,5-Di-Tert-Butylbenzene S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 4-IODO BENZOIC ACID 3-NITRO-2-METHYL ANILINE 1-(2,4-DICHLOROPHENYL) ETHANAMINE (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
N3-PEG3-tBu
20-Azido-3,6,9,12,15,18-hexaoxaeicosan-1-amine
17-Azido-3,6,9,12,15-pentaoxaheptadecan-1-amine
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Amino-PEG8-azide
3,6,9,12,15-PENTAOXAHEPTADECANE-1,17-DIYL BIS-AZIDE
N3-PEG4-tBu
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