H2N-PEG8-tBu
- CAS NO.:756526-06-4
- Empirical Formula: C23H47NO10
- Molecular Weight: 497.62
- MDL number: MFCD11041142
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:13
What is H2N-PEG8-tBu?
Description
Amino-PEG8-t-butyl ester is a monodisperse PEG linker containing an amino group with a t-butyl protected carboxyl group.The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
The Uses of H2N-PEG8-tBu
H2N-PEG8-tBu is a cleavable 8-unit PEG-ADC linker for antibody drug conjugate (ADC) synthesis.
Properties of H2N-PEG8-tBu
Boiling point: | 544.3±45.0 °C(Predicted) |
Density | 1.067±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C(protect from light) |
solubility | Soluble in Water, DMSO, DCM, DMF |
pka | 8.74±0.10(Predicted) |
color | Colorless to light yellow |
Safety information for H2N-PEG8-tBu
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for H2N-PEG8-tBu
New Products
Tubulysin I Tubulysin M Tubulysin G 4,4-DIFLUOROPIPERIDINE 2H-Pyran, 4-ethynyltetrahydro- 3-N-BOC-(S)-AMINO BUTYRONITRILE 1,2,3,6-TETRAHYDROPYRIDINE HYDROCHLORIDE 3-Aminocyclobutanone hydrochloride 2-(azetidin-3-ylidene)acetonitrile (hydrochloride) 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile Imeglimin Hydrochloride IH Fuel shell Magnesium Trisilicate Latanoprostene Bunod Lubiprostone Flame Retardant Zinc Borate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate methyl 3-fluoro-4- thiomorpholino phenylcarbamate 1H-Imidazole-4-carbonitrile 7-Methoxyquinoline-4-carboxylic acid 7-Methoxyquinoline-4-carbonitrileRelated products of tetrahydrofuran
N3-PEG3-tBu
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17-Azido-3,6,9,12,15-pentaoxaheptadecan-1-amine
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AMINO-PEG12-T-BUTYL ESTER
Amino-PEG8-azide
3,6,9,12,15-PENTAOXAHEPTADECANE-1,17-DIYL BIS-AZIDE
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