Glyoxylic acid monohydrate

Synonym(s):Formylformic acid;Glyoxylic acid monohydrate;Oxoethanoic acid

CAS NO.：563-96-2
Empirical Formula: C2H4O4
Molecular Weight: 92.05
MDL number: MFCD00006958
EINECS: 679-230-4
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-04 20:04:50

What is Glyoxylic acid monohydrate?

Chemical properties

white to light yellow crystalline powder or chunks

The Uses of Glyoxylic acid monohydrate

Occurs in unripe fruit and in young green leaves; has also been found in very young sugar beets.

The Uses of Glyoxylic acid monohydrate

Glyoxylic acid is a reagent for sulfinylmaleate synthesis. It is one of the chemicals used in the Hopkins Cole reaction. It is involved to check the presence of tryptophan in proteins. It is condensed with urea and 1,2-diaminobenzene to form heterocycles. It also undergoes Friedel-Crafts and cyclocondensation reactions to form bis(pentamethylphenyl) acetic acid and a beta-carboline respectively. It is employed in the synthesis of a sulfinylmaleate, which serves as an efficient dienophile for enantioselective Diels-Alder cycloadditions.

What are the applications of Application

Glyoxylic acid monohydrate is a reagent for sulfinylmaleate synthesis

Properties of Glyoxylic acid monohydrate

Melting point:	49-52 °C(lit.)
Boiling point:	100 °C(lit.)
Density	1.33 g/mL at 20 °C
refractive index	n20/D 1.414
Flash point:	>230 °F
storage temp.	Store below +30°C.
solubility	H₂O: 0.1 g/mL, clear
form	Liquid
pka	3.43±0.11(Predicted)
color	White to light yellow
Water Solubility	Freely soluble
Sensitive	Hygroscopic
Merck	14,4511
BRN	969535
CAS DataBase Reference	563-96-2(CAS DataBase Reference)

Safety information for Glyoxylic acid monohydrate

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H290:Corrosive to Metals H315:Skin corrosion/irritation H317:Sensitisation, Skin H318:Serious eye damage/eye irritation
Precautionary Statement Codes	P234:Keep only in original container. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.