Ethyl glyoxalate
- CAS NO.：924-44-7
- Empirical Formula: C4H6O3
- Molecular Weight: 102.09
- MDL number: MFCD00044009
- EINECS: 213-105-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:08:52
What is Ethyl glyoxalate?
Chemical properties
Clear colorless to slightly yellow solution
The Uses of Ethyl glyoxalate
Ethyl glyoxylate is widely used as an intermediate in the synthesis of pharmaceuticals (high reactivity of aldehyde function). It is used in the synthesis of a biodegradable polymer, poly(ethyl glyoxylate). It is actively involved in the Friedel-Crafts alkylation reactions with thiophenes to give the corresponding secondary alcohols.
Definition
ChEBI: The ethyl ester of glyoxylic acid.
Synthesis Reference(s)
Tetrahedron Letters, 24, p. 2223, 1983 DOI: 10.1016/S0040-4039(00)81889-4
Properties of Ethyl glyoxalate
| Boiling point: | 110°C |
| Density | 1.03 g/mL at 20 °C |
| refractive index | 1.4750 |
| Flash point: | 7°C |
| storage temp. | Refrigerator |
| solubility | Chloroform, Ethyl Acetate |
| form | Oil |
| color | Clear Colorless |
| Water Solubility | Immiscible with water. |
| Sensitive | Air Sensitive |
| BRN | 1209486 |
| CAS DataBase Reference | 924-44-7(CAS DataBase Reference) |
| EPA Substance Registry System | Acetic acid, oxo-, ethyl ester (924-44-7) |
Safety information for Ethyl glyoxalate
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07  Health Hazard GHS08 |
| GHS Hazard Statements |
H225:Flammable liquids H315:Skin corrosion/irritation H317:Sensitisation, Skin |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P308+P313:IF exposed or concerned: Get medical advice/attention. |
Computed Descriptors for Ethyl glyoxalate
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