Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name listGLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN

GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN

Synonym(s):Preproglucagon 78-107 Amide

GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN Structural

What is GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN?

The Uses of GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN

Diabetes?II?-?not?yet?an?approved?application

The Uses of GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN

Glucagon-Like Peptide-1 is used as a Effector in the hormonal control of insulin secretion. The peptide fragment is secreted from the lower small intestine. Its action is mediated by receptors expressed by the endocrine pancreatic B-cells.

The Uses of GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN

Glucagon-Like Peptide (GLP) I Amide Fragment 7-36 human has been used as a GLP-1 receptor agonist:

  • in lysate transfer cyclic adenosine monophosphate (cAMP) assay to test its effect on adenylyl cyclase activity
  • to pre-treat the human umbilical vein endothelial cells (HUVECs) to monitor its effect on hyperpermeability in endothelial cell (EC) monolayers and changes with the actin cytoskeleton
  • to test its inhibitory effect on vascular endothelial growth factor-A (VEGFA) based vasodilation in rat mesenteric arteries

What are the applications of Application

Glucagon-Like Peptide 1 (7-36) Amide is a potent insulinotropic peptide

General Description

Glucagon-like peptide 1 (GLP-1) peptide is obtained from proglucagon and is metabolically inactive. However, it is processed to two smaller amide forms, namely GLP-1 (7-37) amide and GLP-1 (7-36) amide. It is a natural gastrointestinal peptide.

Biochem/physiol Actions

GLP-1 (glucagon-like peptide 1) (7-36) amide is a potent insulinotropic peptide, which initiates the glucose-induced insulin release after meals or oral glucose intake. It has an anti-diabetogenic effect and thus, might have use in the treatment of non-insulin dependent diabetes mellitus.

storage

Store at -20°C

Properties of GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN

Density  1.47
RTECS  LZ3980060
storage temp.  −20°C
solubility  Soluble in DMSO
form  powder
Water Solubility  Soluble in water (1 mg/ml).

Safety information for GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN

Computed Descriptors for GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN

InChIKey DTHNMHAUYICORS-KTKZVXAJSA-N

Related products of tetrahydrofuran

You may like

  • Glucagon-Like Peptide I Amide Fragment 7-36 human CAS 107444-51-9
    Glucagon-Like Peptide I Amide Fragment 7-36 human CAS 107444-51-9
    107444-51-9
    View Details
  • 1-Methyl-6-oxo-1,6-dihydropyridazine-3-carbonitrile 98%
    1-Methyl-6-oxo-1,6-dihydropyridazine-3-carbonitrile 98%
    99903-60-3
    View Details
  • 1823368-42-8 98%
    1823368-42-8 98%
    1823368-42-8
    View Details
  • 2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%
    2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%
    1307449-08-6
    View Details
  • Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%
    Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%
    25408-95-1
    View Details
  • 2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%
    2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%
    1805639-70-6
    View Details
  • 1784294-80-9 98%
    1784294-80-9 98%
    1784294-80-9
    View Details
  • Lithium Clavulanate
    Lithium Clavulanate
    61177-44-4
    View Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.