gemcitabine
- CAS NO.:103882-84-4
- Empirical Formula: C9H11F2N3O4
- Molecular Weight: 263.2
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 10:43:58
What is gemcitabine?
The Uses of gemcitabine
Gemcitabine is a nucleoside analog with anti-cancer properties. An inhibitor of DNA synthesis active on solid tumors.
What are the applications of Application
Gemcitabine is a nucleoside analog with anti-cancer properties
Definition
ChEBI: Gemcitabine is a 2'-deoxycytidine having geminal fluoro substituents in the 2'-position. An inhibitor of ribonucleotide reductase, gemcitabine is used in the treatment of various carcinomas, particularly non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer. It has a role as a photosensitizing agent, a DNA synthesis inhibitor, a prodrug, an EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor, an environmental contaminant, a xenobiotic, a radiosensitizing agent, an antineoplastic agent, an antimetabolite, an antiviral drug and an immunosuppressive agent. It is an organofluorine compound and a pyrimidine 2'-deoxyribonucleoside.
Properties of gemcitabine
Boiling point: | 482.7±55.0 °C(Predicted) |
Density | 1.4034 (estimate) |
solubility | DMSO (Slightly), Methanol (Slightly) |
pka | 11.65±0.70(Predicted) |
form | Solid |
color | White |
Safety information for gemcitabine
Computed Descriptors for gemcitabine
New Products
6-Bromo 2-Iodo Indole Rimegepant Impurity 3 Ivermectin EP Impurity B Fosfomycin EP impurity D Tubulysin C Tubulysin I Tubulysin B Tubulysin G (R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile Calcium Sodium Phosphosilicate IH 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Imeglimin Hydrochloride IH 2-Ethoxy-4-nitrobenzoic acid 4-(Azidomethyl)-3-chloropyridine 3-Morpholino-1-[4-(2-oxo-1-piperidyl)phenyl]-5,6-dihydropyridin-2(1H)-one Methyl 4-amino-3-(dihexylamino)benzoate 2-(3,5-Di-tert-butylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione 2,2-dibromopropanoate 2-(Tert-butoxycarbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid 6-Bromo-2-methoxy-3-(4-methyl-1H-imidazol-1-yl)pyridineRelated products of tetrahydrofuran
You may like
-
3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dioneView Details
952145-70-9 -
452-58-4View Details
452-58-4 -
1262243-12-8View Details
1262243-12-8 -
65195-56-4View Details
65195-56-4 -
Rimegepant Impurity 3View Details
-
Sidchem 730View Details
-
Sidchem BT 20View Details
-
1572177-89-9View Details
1572177-89-9