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HomeProduct name listGamma-mangostin

Gamma-mangostin

Synonym(s):1,3,6,7-Tetrahydroxy-2,8-bis(3,3-dimethylallyl)xanthone;Demethylmangostin;Normangostin

Gamma-mangostin Structural

What is Gamma-mangostin?

The Uses of Gamma-mangostin

Gamma-Mangostin is a xanthones which displays anti-oxidant properties and could be a promising compound for the therapy of AlzheimerтАЩs disease.

Definition

ChEBI: A member of the class of xanthones that is 9H-xanthene substituted by hydroxy group at positions 1, 3, 6 and 7, an oxo group at position 9 and prenyl groups at positions 2 and 8. Isolated from the stems of Cratoxylum cochinchinense /ital>, it exhibits antitumour activity.

References

[1] Takeshi Yokoyama. “Discovery of γ-Mangostin as an Amyloidogenesis Inhibitor.” Scientific Reports (2015): 13570.

Properties of Gamma-mangostin

Melting point: 206-208 °C
Boiling point: 648.4±55.0 °C(Predicted)
Density  1.326±0.06 g/cm3(Predicted)
storage temp.  2-8°C
solubility  methanol: soluble1mg/mL, colorless to yellow
form  powder
pka 7.05±0.20(Predicted)
color  off-white to yellow
InChI InChI=1S/C23H24O6/c1-11(2)5-7-13-15(24)9-18-20(22(13)27)23(28)19-14(8-6-12(3)4)21(26)16(25)10-17(19)29-18/h5-6,9-10,24-27H,7-8H2,1-4H3

Safety information for Gamma-mangostin

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral

Computed Descriptors for Gamma-mangostin

InChIKey VEZXFTKZUMARDU-UHFFFAOYSA-N
SMILES C1(=O)C2=C(C=C(O)C(O)=C2C/C=C(/C)\C)OC2=C1C(O)=C(C/C=C(/C)\C)C(O)=C2

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