Gamma-mangostin
Synonym(s):1,3,6,7-Tetrahydroxy-2,8-bis(3,3-dimethylallyl)xanthone;Demethylmangostin;Normangostin
- CAS NO.：31271-07-5
- Empirical Formula: C23H24O6
- Molecular Weight: 396.43
- MDL number: MFCD00951752
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-05 08:26:49
What is Gamma-mangostin?
The Uses of Gamma-mangostin
Gamma-Mangostin is a xanthones which displays anti-oxidant properties and could be a promising compound for the therapy of AlzheimerтАЩs disease.
Definition
ChEBI: A member of the class of xanthones that is 9H-xanthene substituted by hydroxy group at positions 1, 3, 6 and 7, an oxo group at position 9 and prenyl groups at positions 2 and 8. Isolated from the stems of Cratoxylum cochinchinense /ital>, it exhibits antitumour activity.
References
[1] Takeshi Yokoyama. “Discovery of γ-Mangostin as an Amyloidogenesis Inhibitor.” Scientific Reports (2015): 13570.
Properties of Gamma-mangostin
| Melting point: | 206-208 °C |
| Boiling point: | 648.4±55.0 °C(Predicted) |
| Density | 1.326±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | methanol: soluble1mg/mL, colorless to yellow |
| form | powder |
| pka | 7.05±0.20(Predicted) |
| color | off-white to yellow |
| InChI | InChI=1S/C23H24O6/c1-11(2)5-7-13-15(24)9-18-20(22(13)27)23(28)19-14(8-6-12(3)4)21(26)16(25)10-17(19)29-18/h5-6,9-10,24-27H,7-8H2,1-4H3 |
Safety information for Gamma-mangostin
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
Computed Descriptors for Gamma-mangostin
| InChIKey | VEZXFTKZUMARDU-UHFFFAOYSA-N |
| SMILES | C1(=O)C2=C(C=C(O)C(O)=C2C/C=C(/C)\C)OC2=C1C(O)=C(C/C=C(/C)\C)C(O)=C2 |
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