2,2',4,4'-Tetrahydroxybenzophenone

CAS NO.：131-55-5
Empirical Formula: C13H10O5
Molecular Weight: 246.22
MDL number: MFCD00002278
EINECS: 205-028-9
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-04 20:04:50

What is 2,2',4,4'-Tetrahydroxybenzophenone?

Chemical properties

yellow to brown crystalline powder

The Uses of 2,2',4,4'-Tetrahydroxybenzophenone

2,2',4,4'-Tetrahydroxybenzophenone is a uV-absorber that helps protect against product degradation because of uV-light exposure. It can also mask odor associated with a formulation’s composition.

The Uses of 2,2',4,4'-Tetrahydroxybenzophenone

2,2′,4,4′-Tetrahydroxybenzophenone are benzophenone-type UV filters with known or suspected endocrine disrupting properties detected in surface waters, sunscreens, personal care products, clothing and food packaging. It is used to protect the skin and materials from the adverse effects of UV-radiation.

The Uses of 2,2',4,4'-Tetrahydroxybenzophenone

2,2',4,4'-Tetrahydroxybenzophenone is used as the raw material of ultraviolet absorbers in cosmetics, plastics, resins and rubber. It is used as pharmaceutical intermediates and light-sensitive materials. It is also used as pharmaceutical adjuvant.

Preparation

Obtained (small amount) by melting a fluorescin chloride/sodium hydroxide mixture in the presence of a very few water at 230–240° for 2–3 h.

Contact allergens

BZP-2 is widely used in perfumes to prevent their degradation due to light. It can cause allergic contact dermatitis.

Safety Profile

Moderately toxic by ingestion. Aneye irritant. Mutation data reported. When heated todecomposition it emits toxic fumes of NOx.

Properties of 2,2',4,4'-Tetrahydroxybenzophenone

Melting point:	198-200 °C(lit.)
Boiling point:	349.21°C (rough estimate)
Density	1.216
refractive index	1.4825 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO (Slightly, Sonicated), Methanol (Slightly)
form	Solid
pka	6.98±0.35(Predicted)
color	Needles from H2O
Water Solubility	Slightly soluble in water.
BRN	1914746
Stability:	Hygroscopic
CAS DataBase Reference	131-55-5(CAS DataBase Reference)
NIST Chemistry Reference	2,2',4,4'-Tetrahydroxybenzophenone(131-55-5)
EPA Substance Registry System	2,2',4,4'-Tetrahydroxybenzophenone (131-55-5)

Safety information for 2,2',4,4'-Tetrahydroxybenzophenone

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H317:Sensitisation, Skin H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.