Fmoc-S-Trityl-L-penicillamine
Synonym(s):Fmoc-α, α-dimethyl-Cys(Trt)-OH,Fmoc-S-trityl-L-penicillamine;Fmoc-β,β-dimethyl-Cys(Trt)-OH;Fmoc-S-trityl-L -penicillamine;Fmoc-Pen(Trt)-OH
- CAS NO.：201531-88-6
- Empirical Formula: C39H35NO4S
- Molecular Weight: 613.76
- MDL number: MFCD00237388
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-04-24 17:21:45
What is Fmoc-S-Trityl-L-penicillamine?
Description
Fmoc-S-trityl-L-penicillamine is a coordination compound that contains a thiolate and amide group. It has been used as a model system for studying the interaction between proteins and metal ions, with the cyclic structure mimicking the active site of enzymes. The coordination of Fmoc-S-trityl-L-penicillamine to proteins is affected by trypsin, an enzyme that cleaves peptides at carboxyl side chains. Trypsin can also lead to dehydration of Fmoc-S-trityl-L-penicillamine, forming an eliminations product. This compound also reacts with lysine residues in proteins, resulting in an alkene byproduct that can be removed by hydrogenation.
Chemical properties
White to off-white powder
The Uses of Fmoc-S-Trityl-L-penicillamine
Fmoc-s-trityl-l-penicillamine is a new peptidomimetic furin inhibitors with potent anti-infectious activity.
What are the applications of Application
Fmoc-Pen(Trt)-OH is an Fmoc protected amino acid derivative
Properties of Fmoc-S-Trityl-L-penicillamine
| Boiling point: | 768.8±60.0 °C(Predicted) |
| alpha | 33 º (c=1 in methanol) |
| Density | 1.242±0.06 g/cm3(Predicted) |
| storage temp. | Store at -15°C to -25°C. |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Powder |
| pka | 3.70±0.10(Predicted) |
| optical activity | [α]/D +33±2°, c = 1 in methanol |
| CAS DataBase Reference | 201531-88-6(CAS DataBase Reference) |
Safety information for Fmoc-S-Trityl-L-penicillamine
Computed Descriptors for Fmoc-S-Trityl-L-penicillamine
| InChIKey | XSGMGAINOILNJR-PGUFJCEWSA-N |
| SMILES | C(O)(=O)[C@H](C(SC(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1)(C)C)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O |
New Products
Tert-butyl bis(2-chloroethyl)carbamate 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid 1,1’-CARBONYLDIIMIDAZOLE DIETHYL AMINOMALONATE HYDROCHLORIDE R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 2-aminopropyl benzoate hydrochloride 1-(4-(aminomethyl)benzyl)urea hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
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