(-)-2-[METHYLAMINO]-1-PHENYLPROPANE
Synonym(s):levo-Methamphetamine
- CAS NO.：33817-09-3
- Empirical Formula: C10H15N
- Molecular Weight: 149.24
- MDL number: MFCD00135973
- EINECS: 251-687-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 10:44:00
![(-)-2-[METHYLAMINO]-1-PHENYLPROPANE Structural](https://img.chemicalbook.in/CAS/GIF/33817-09-3.gif)
What is (-)-2-[METHYLAMINO]-1-PHENYLPROPANE?
The Uses of (-)-2-[METHYLAMINO]-1-PHENYLPROPANE
Nasal decongestant.
Indications
Used over-the-counter for nasal congestion.
Background
Levomethamphetamine, the L-enantiomer of methamphetamine is a sympathomimetic vasoconstrictor used in some over-the-counter (OTC) nasal decongestant inhalers in the United States.
Definition
ChEBI: Levmetamfetamine is a member of amphetamines.
Synthesis Reference(s)
The Journal of Organic Chemistry, 37, p. 2208, 1972 DOI: 10.1021/jo00978a034
General Description
R(-)-Methamphetamine, or levomethamphetamine, is a vasoconstrictor and component of multiple over-the-counter nasal decongestants. This certified Snap-N-Spike? solution is suitable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications such as forensic analysis, sports testing, clinical toxicology, or urine drug testing. R(-)-Methamphetamine belongs to the amphetamine and phenethylamine classes of drugs.
Pharmacokinetics
Levomethamphetamine increases norepinephrine release resulting in increased vasocontriction.
Metabolism
Not Available
Properties of (-)-2-[METHYLAMINO]-1-PHENYLPROPANE
| Melting point: | 38-40 °C |
| Boiling point: | 104-107 °C(Press: 28 Torr) |
| Density | 0.907±0.06 g/cm3(Predicted) |
| Flash point: | 9℃ |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Ethanol (Slightly), Methanol (Sparingly) |
| pka | pKa 9.99(H2O,t =25±0.5,I=0.01)(Approximate) |
| form | Oil |
| color | Pale Yellow |
Safety information for (-)-2-[METHYLAMINO]-1-PHENYLPROPANE
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H319:Serious eye damage/eye irritation H361:Reproductive toxicity |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P403+P233:Store in a well-ventilated place. Keep container tightly closed. |
Computed Descriptors for (-)-2-[METHYLAMINO]-1-PHENYLPROPANE
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