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HomeProduct name list(-)-2-[METHYLAMINO]-1-PHENYLPROPANE

(-)-2-[METHYLAMINO]-1-PHENYLPROPANE

Synonym(s):levo-Methamphetamine

  • CAS NO.:33817-09-3
  • Empirical Formula: C10H15N
  • Molecular Weight: 149.24
  • MDL number: MFCD00135973
  • EINECS: 251-687-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-05-15 10:44:00
(-)-2-[METHYLAMINO]-1-PHENYLPROPANE Structural

What is (-)-2-[METHYLAMINO]-1-PHENYLPROPANE?

The Uses of (-)-2-[METHYLAMINO]-1-PHENYLPROPANE

Nasal decongestant.

Indications

Used over-the-counter for nasal congestion.

Background

Levomethamphetamine, the L-enantiomer of methamphetamine is a sympathomimetic vasoconstrictor used in some over-the-counter (OTC) nasal decongestant inhalers in the United States.

Definition

ChEBI: Levmetamfetamine is a member of amphetamines.

Synthesis Reference(s)

The Journal of Organic Chemistry, 37, p. 2208, 1972 DOI: 10.1021/jo00978a034

General Description

R(-)-Methamphetamine, or levomethamphetamine, is a vasoconstrictor and component of multiple over-the-counter nasal decongestants. This certified Snap-N-Spike? solution is suitable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications such as forensic analysis, sports testing, clinical toxicology, or urine drug testing. R(-)-Methamphetamine belongs to the amphetamine and phenethylamine classes of drugs.

Pharmacokinetics

Levomethamphetamine increases norepinephrine release resulting in increased vasocontriction.

Metabolism

Not Available

Properties of (-)-2-[METHYLAMINO]-1-PHENYLPROPANE

Melting point: 38-40 °C
Boiling point: 104-107 °C(Press: 28 Torr)
Density  0.907±0.06 g/cm3(Predicted)
Flash point: 9℃
storage temp.  2-8°C
solubility  Chloroform (Slightly), Ethanol (Slightly), Methanol (Sparingly)
pka pKa 9.99(H2O,t =25±0.5,I=0.01)(Approximate)
form  Oil
color  Pale Yellow

Safety information for (-)-2-[METHYLAMINO]-1-PHENYLPROPANE

Signal word Danger
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
ghs
Health Hazard
GHS08
GHS Hazard Statements H319:Serious eye damage/eye irritation
H361:Reproductive toxicity
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P403+P233:Store in a well-ventilated place. Keep container tightly closed.

Computed Descriptors for (-)-2-[METHYLAMINO]-1-PHENYLPROPANE

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