FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE
- CAS NO.:1013883-02-7
- Empirical Formula: C31H34N2O7
- Molecular Weight: 546.61
- MDL number: MFCD07781260
- Update Date: 2023-05-04 15:15:58
![FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE Structural](https://img.chemicalbook.in/StructureFile/ChemBookStructure9/GIF/CB0432276.gif)
What is FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE?
The Uses of FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE
FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.
Synthesis
Add O-[2-[[tert-butoxycarbonyl]amino]ethyl]-L-tyrosine (3.24g, 10mmol) in a 100mL three-necked flask equipped with magnetic stirring and a thermometer, with a mass concentration of 5 · 5% 21.2g of sodium carbonate aqueous solution, 20mL of 9-fluorenylmethyl-N-succinimidyl carbonate (3.37g, 10mmol) in tetrahydrofuran solution was added dropwise at room temperature, after the addition, the amidation reaction was carried out at room temperature, monitored by TLC To the end of the reaction. Concentrated to remove part of the solvent, acidified with 2N hydrochloric acid to pH 6~7, extracted with ethyl acetate, washed with saturated brine, concentrated, beaten with petroleum ether, filtered and dried to obtain a white solid O-alkyl-N-[ Fluorenylmethyloxycarbonyl]-L-tyrosine is 4.68g, the yield is 85.7%, the HPLC purity is 99.8%, and the ee value is 99.8%.
Properties of FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE
Boiling point: | 759.1±60.0 °C(Predicted) |
Density | 1.245±0.06 g/cm3(Predicted) |
pka | 2.96±0.10(Predicted) |
Safety information for FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE
Computed Descriptors for FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE
New Products
3,5-Dichloro2,4,6-trifloro pyridine 6-Bromo-2-Methoxy quinolie 4-Bromo-2,6-dimethyl-benzaldehyde 2-amino 3,5-Dibromo benzaldehyde ( ADBA) 4-Chloro-4-Hydroxybenzophenone 3,5-Dinitrobenzotrifluoride Dorzolamide Hydrochloride Fluconazole Lidocaine Hydrochloride 3 Methoxy Benzoic Acid Ketoconazole Sodium Stannate 2,2-diethoxyacetamide Tubulysin C (R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate Tubulysin I Tubulysin B Tubulysin D SULPHO RHODAMINE PYRANINE D&C EXT. VIOLET 2 FAST GREEN FCF EOSIN Y BRILLIANT BLUE FCF (90%)Related products of tetrahydrofuran
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