Fmoc-N'-methyltrityl-L-lysine
Synonym(s):Fmoc-Lys(Mmt)-OH;Fmoc-Lys(Mtt)-OH;N-α-Fmoc-N-ε-4-methoxytrityl-L-lysine;N-α-Fmoc-N-ε-4-methyltrityl-L-lysine
- CAS NO.：167393-62-6
- Empirical Formula: C41H40N2O4
- Molecular Weight: 624.77
- MDL number: MFCD00237166
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is Fmoc-N'-methyltrityl-L-lysine?
Chemical properties
White to off-white powder
The Uses of Fmoc-N'-methyltrityl-L-lysine
Fmoc-Lys(Mtt)-OH, is an amino acid derivative, used in chemical synthesis and peptide chemistry.
General Description
The side-chain Mtt group can be selectively removed with 1% TFA in DCM [1, 2, 3] or DCM/HFIP/TFE/TES (6.5:2:1:0.5) [4], making this an excellent derivative for the synthesis of branched peptides, peptides modified at the lysine side-chain [5,6], for the construction of templates and multifunctionalized resins for combinatorial synthesis.
The product number for this product was previously 04-12-1137.
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Properties of Fmoc-N'-methyltrityl-L-lysine
| Melting point: | 140 °C(dec.) |
| Boiling point: | 798.8±60.0 °C(Predicted) |
| Density | 1?+-.0.06 g/cm3(Predicted) |
| storage temp. | Store at +2°C to +8°C. |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Solid |
| pka | 3.83±0.21(Predicted) |
| color | White to Almost white |
| CAS DataBase Reference | 167393-62-6(CAS DataBase Reference) |
Safety information for Fmoc-N'-methyltrityl-L-lysine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Fmoc-N'-methyltrityl-L-lysine
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