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HomeProduct name listFMoc-N-Me-Cys(Trt)-OH

FMoc-N-Me-Cys(Trt)-OH

Synonym(s):Fmoc-N-Me-Cys(Trt)-OH;N-α-Fmoc-N-α-methyl-S-trityl-L-cysteine

FMoc-N-Me-Cys(Trt)-OH Structural

What is FMoc-N-Me-Cys(Trt)-OH?

The Uses of FMoc-N-Me-Cys(Trt)-OH

Fmoc-N-Me-L-Cys(Trt)-OH (CAS# 944797-51-7) is an fmoc- and trityl-protected derivative of L-cysteine (C995000) used as a building block for peptides or peptide fragments, such as the solid-phase synthesis of Triostin A.

The Uses of FMoc-N-Me-Cys(Trt)-OH

Fmoc-N-Me-Cys(Trt)-OH is a Fmoc-protected derivative of N-methyl cysteine used as a building block to prepare peptide thioesters under acidic conditions. The residue attached to the amino group of N-methylcysteine can migrate to the cysteinyl thiol group, resulting in the formation of a peptide thioester. The introduction of this Fmoc-protected derivative is best achieved using HATU as a coupling reagent in the presence of DIPEA (N, N-Diisopropylethylamine).
It can also be used to prepare Fmoc-N-Me-Cys(Trt)-OAllyl intermediate for the solid-phase synthesis of dithiol Triostin A.

Properties of FMoc-N-Me-Cys(Trt)-OH

Melting point: 234-239°C
Boiling point: 746.0±60.0 °C(Predicted)
Density  1.260±0.06 g/cm3(Predicted)
storage temp.  Store at -15°C to -25°C.
form  Solid
pka 3.72±0.10(Predicted)
color  White to off-white
optical activity [α]22/D -25.0°, c = 0.5% in dichloromethane

Safety information for FMoc-N-Me-Cys(Trt)-OH

Computed Descriptors for FMoc-N-Me-Cys(Trt)-OH

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