Fmoc-L-tert-leucine
Synonym(s):Fmoc-α-t-butylglycine;Fmoc-L -tert-leucine;Fmoc-Tle-OH;N-α-Fmoc-L-α-t.-butyl-glycine, Fmoc-Tle-OH
- CAS NO.：132684-60-7
- Empirical Formula: C21H23NO4
- Molecular Weight: 353.41
- MDL number: MFCD00065649
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-11-29 17:10:20
What is Fmoc-L-tert-leucine?
Chemical properties
solid
The Uses of Fmoc-L-tert-leucine
Fmoc-Tle-OH is a versatile reactant used in the discovery of potent antagonists of antiapoptotic protein X-linked inhibitor of apoptosis (XIAP) for treatment of cancer. It is also used as reactant in the preparation of phosphino dipeptide derivatices as ligand in copper-phosphine catalyst for asymmetric conjugate addition of alkylzinc reagents to unsaturated ketones.
What are the applications of Application
Fmoc-tBu-Gly-OH is an Fmoc protected glycine derivative
Properties of Fmoc-L-tert-leucine
| Melting point: | 124-127 °C |
| Boiling point: | 554.1±33.0 °C(Predicted) |
| Density | 1.209±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | ≥ 35.3mg/mL in DMSO, ≥ 49.6 mg/mL in EtOH |
| pka | 3.92±0.10(Predicted) |
| form | powder to crystal |
| color | White to Light yellow |
| BRN | 6662856 |
| CAS DataBase Reference | 132684-60-7(CAS DataBase Reference) |
Safety information for Fmoc-L-tert-leucine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Fmoc-L-tert-leucine
New Products
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