Fmoc-D-leucine
Synonym(s):Fmoc-D -leucine;Fmoc-D-Leu-OH;N-α-Fmoc-D-leucine
- CAS NO.：114360-54-2
- Empirical Formula: C21H23NO4
- Molecular Weight: 353.41
- MDL number: MFCD00062957
- EINECS: 252-662-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-12-01 17:57:45
What is Fmoc-D-leucine?
Chemical properties
White powder
The Uses of Fmoc-D-leucine
A convergent synthesis of the proposed structure of (+)-pestalazine B has been achieved in 4 steps using the N-alkylation of an unprotected tryptophan diketopiperazine with a 3a-bromopyrrolidinoindoline where the condensation between L-tryptophan methyl ester and N-Fmoc-D-leucine in the presence of EDC as coupling agent afforded the corresponding L-Trp-D-Leu dipeptide.
What are the applications of Application
N-Fmoc-D-leucine is a Fmoc-protected leucine derivative
Definition
ChEBI: Fmoc-D-Leu-OH is a leucine derivative.
Properties of Fmoc-D-leucine
| Melting point: | 155°C |
| Boiling point: | 559.8±33.0 °C(Predicted) |
| Density | 1?+-.0.06 g/cm3(Predicted) |
| refractive index | 25 ° (C=1, DMF) |
| storage temp. | 2-8°C |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| pka | 3.91±0.21(Predicted) |
| form | powder to crystal |
| color | White to Almost white |
| Water Solubility | Insoluble in water. |
| CAS DataBase Reference | 114360-54-2(CAS DataBase Reference) |
Safety information for Fmoc-D-leucine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H413:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Fmoc-D-leucine
Fmoc-D-leucine manufacturer
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