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HomeProduct name listFmoc-D-leucine

Fmoc-D-leucine

Synonym(s):Fmoc-D-leucine;Fmoc-D-Leu-OH;N-α-Fmoc-D-leucine

  • CAS NO.:114360-54-2
  • Empirical Formula: C21H23NO4
  • Molecular Weight: 353.41
  • MDL number: MFCD00062957
  • EINECS: 252-662-7
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-12-01 17:57:45
Fmoc-D-leucine Structural

What is Fmoc-D-leucine?

Chemical properties

White powder

The Uses of Fmoc-D-leucine

A convergent synthesis of the proposed structure of (+)-pestalazine B has been achieved in 4 steps using the N-alkylation of an unprotected tryptophan diketopiperazine with a 3a-bromopyrrolidinoindoline where the condensation between L-tryptophan methyl ester and N-Fmoc-D-leucine in the presence of EDC as coupling agent afforded the corresponding L-Trp-D-Leu dipeptide.

What are the applications of Application

N-Fmoc-D-leucine is a Fmoc-protected leucine derivative

Definition

ChEBI: Fmoc-D-Leu-OH is a leucine derivative.

Properties of Fmoc-D-leucine

Melting point: 155°C
Boiling point: 559.8±33.0 °C(Predicted)
Density  1?+-.0.06 g/cm3(Predicted)
refractive index  25 ° (C=1, DMF)
storage temp.  2-8°C
solubility  Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka 3.91±0.21(Predicted)
form  powder to crystal
color  White to Almost white
Water Solubility  Insoluble in water.
CAS DataBase Reference 114360-54-2(CAS DataBase Reference)

Safety information for Fmoc-D-leucine

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
H413:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Fmoc-D-leucine

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