Nalpha-Fmoc-Ndelta-trityl-L-glutamine
Synonym(s):Nα-Fmoc-Nδ-trityl-L -glutamine;Fmoc-Gln(Trt)-OH;N-α-Fmoc-N-γ-trityl-L-glutamine
- CAS NO.：132327-80-1
- Empirical Formula: C39H34N2O5
- Molecular Weight: 610.7
- MDL number: MFCD00077056
- EINECS: 603-564-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-02 17:19:06
What is Nalpha-Fmoc-Ndelta-trityl-L-glutamine?
Chemical properties
white to light yellow crystal powde
The Uses of Nalpha-Fmoc-Ndelta-trityl-L-glutamine
Fmoc-Gln(trt)-OH, is an amino acid derivative used in chemical synthesis and peptide chemistry.
General Description
Fmoc-Gln(Trt)-OH has good solubility properties in most organic solvents, and its use has been shown to result in significantly purer peptides than other derivatives used for the introduction of Gln [1]. Coupling can be performed by standard procedures. The trityl-protecting group is normally removed by 95% TFA in 1-3 hours, with no alkylation of Trp.
The product number for this product was previously 04-12-1090.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.
Properties of Nalpha-Fmoc-Ndelta-trityl-L-glutamine
| Melting point: | 165-172 °C |
| Boiling point: | 873.5±65.0 °C(Predicted) |
| Density | 1.256±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Powder |
| pka | 3.73±0.10(Predicted) |
| color | White to yellow |
| optical activity | [α]/D -14.0±1.5°, c = 1% in DMF |
| Sensitive | Moisture Sensitive |
| BRN | 4343953 |
| CAS DataBase Reference | 132327-80-1(CAS DataBase Reference) |
Safety information for Nalpha-Fmoc-Ndelta-trityl-L-glutamine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H317:Sensitisation, Skin H413:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P321:Specific treatment (see … on this label). P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. |
Computed Descriptors for Nalpha-Fmoc-Ndelta-trityl-L-glutamine
| InChIKey | WDGICUODAOGOMO-DHUJRADRSA-N |
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