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HomeProduct name listFMOC-12-AMINODODECANOIC ACID

FMOC-12-AMINODODECANOIC ACID

Synonym(s):12-(Fmoc-amino)dodecanoic acid

FMOC-12-AMINODODECANOIC ACID Structural

What is FMOC-12-AMINODODECANOIC ACID?

Description

Fmoc-12-aminododecanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Chemical properties

White to off-white powder

The Uses of FMOC-12-AMINODODECANOIC ACID

12-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)dodecanoic Acid has been used as a reactant for the preparation of pro-apoptotic peptide functionalized gold nanoparticles as a new anti-cancer strategy of damaging mitochondria.

Properties of FMOC-12-AMINODODECANOIC ACID

Melting point: 102 °C
Boiling point: 628.8±28.0 °C(Predicted)
Density  1.119±0.06 g/cm3(Predicted)
storage temp.  2-8°C
pka 4.78±0.10(Predicted)
BRN  9593537

Safety information for FMOC-12-AMINODODECANOIC ACID

Computed Descriptors for FMOC-12-AMINODODECANOIC ACID

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