12-AMINODODECANOIC ACID
Synonym(s):12-Aminolauric acid
- CAS NO.：693-57-2
- Empirical Formula: C12H25NO2
- Molecular Weight: 215.33
- MDL number: MFCD00008153
- EINECS: 211-754-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:07:02
What is 12-AMINODODECANOIC ACID?
Description
12-Aminododecanoic acid is an alkane chain with terminal carboxlic acid and amine groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.
Chemical properties
Light beige powder
The Uses of 12-AMINODODECANOIC ACID
12-Aminolauric Acid is an amino acid used as a reagent in organic synthesis of several compounds including phenylbutazone which is a new long-acting agent which displays improved pharmacokinectics based on human serum albumin as a drug carrier.
Definition
ChEBI: 12-aminododecanoic acid is an omega-amino fatty acid that is dodecanoic acid in which one of the terminal amino hydrogens has been replaced by an amino group. It has a role as a bacterial metabolite. It is an omega-amino fatty acid and a medium-chain fatty acid.
Flammability and Explosibility
Non flammable
Properties of 12-AMINODODECANOIC ACID
| Melting point: | 185-187 °C (lit.) |
| Boiling point: | 349.7±15.0 °C(Predicted) |
| Density | 0.957±0.06 g/cm3(Predicted) |
| vapor pressure | 0Pa at 25℃ |
| Flash point: | 280 °C |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Aqueous Acid (Slightly), Aqueous Base (Slightly) |
| form | Solid |
| pka | pK1: 4.648(+1) (25°C) |
| color | White to Off-White |
| Water Solubility | 137mg/L at 20℃ |
| BRN | 907502 |
| CAS DataBase Reference | 693-57-2(CAS DataBase Reference) |
| EPA Substance Registry System | 12-Aminolauric acid (693-57-2) |
Safety information for 12-AMINODODECANOIC ACID
Computed Descriptors for 12-AMINODODECANOIC ACID
New Products
Tert-butyl bis(2-chloroethyl)carbamate 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid 1,1’-CARBONYLDIIMIDAZOLE DIETHYL AMINOMALONATE HYDROCHLORIDE R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 2-aminopropyl benzoate hydrochloride 1-(4-(aminomethyl)benzyl)urea hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
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