Flutrimazole
Synonym(s):1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole
- CAS NO.：119006-77-8
- Empirical Formula: C22H16F2N2
- Molecular Weight: 346.37
- MDL number: MFCD00865591
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-11 20:33:26
What is Flutrimazole?
Description
Flutrimazole, a novel imidazole antifungal launched in Spain, is indicated for mycosis of the skin. Flutrimazole displays potent broad-spectrum of activity against dematophytes, filamentous fungi and yeasts, saprophytic and pathogenic to animals and humans. Similar to other imidazole and triazole antifungals, flutrimazole exerts its biological function through inhibition of fungal lanosterol 14a-demethylase. Excellent local and systemic tolerance of flutrimazole in patients has been reported.
Chemical properties
White or almost white powder.
Originator
Uriach (Spain)
The Uses of Flutrimazole
Flutrimazole is a new imidazole antifungal agent with anti-inflammatory properties as well.
Definition
ChEBI: An imidazole antifungal agent that is imidazole in which the hydrogen attached to the nitrogen is replaced by a 2,4'-difluorotrityl group. A topical antifungal agent which displays potent broad-spectrum in vitro activity against dermatophytes, filamentous fungi and yeasts.
brand name
Micetal
Properties of Flutrimazole
| Melting point: | 161-166℃ |
| Boiling point: | 457.1±40.0 °C(Predicted) |
| Density | 1.15±0.1 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | Practically insoluble in water, freely soluble in tetrahydrofuran, soluble in methanol. |
| form | neat |
| pka | 6.03±0.34(Predicted) |
| form | Solid |
| color | White to Pale Yellow |
| CAS DataBase Reference | 119006-77-8(CAS DataBase Reference) |
Safety information for Flutrimazole
Computed Descriptors for Flutrimazole
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium 3-Bromopyrazole (3aR,4R,5R,6aS)-hexahydro-5-Triethyl silyloxy-4-((E)-3-oxo-5-phenylpent-1- enyl)cyclopenta[b]furan-2-one. 1-Chlorocarbonyl-4-piperidinopiperidine 1-Bromo-4-phenyl-2-Butanone 4-Amino-2-fluoro-N-methylbenzamide 1,1'-Carbonyldiimidazole SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTIONRelated products of tetrahydrofuran
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