FLAVONE
Synonym(s):2-Phenyl-4H-1-benzopyran-4-one;2-Phenylchromone
- CAS NO.:525-82-6
- Empirical Formula: C15H10O2
- Molecular Weight: 222.24
- MDL number: MFCD00006825
- EINECS: 208-383-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-05 19:05:58
What is FLAVONE?
Chemical properties
white crystalline powder
The Uses of FLAVONE
Flavone is a potentially useful biochemical for cytochrome P450 studies.
What are the applications of Application
Flavone is a potentially useful biochemical for cytochrome P450 studies
Definition
One of a group of flavonoid plant pigments existing as colorless needles, that are insoluble in water and melting at 100C. It fluoresces violet in concentrated sulfuric acid. It can be synthesized. Treatment with alcoholic alkali yields flavanone. The fla
Synthesis Reference(s)
Journal of the American Chemical Society, 79, p. 689, 1957 DOI: 10.1021/ja01560a050
The Journal of Organic Chemistry, 44, p. 497, 1979 DOI: 10.1021/jo01318a005
Tetrahedron Letters, 31, p. 4073, 1990 DOI: 10.1016/S0040-4039(00)94503-9
Metabolism
Not Available
Purification Methods
Dissolve it in dilute aqueous NaOH, filter and precipitate it by adding dilute (1:1) HCl. The process is repeated twice more, and the fluorescein is dried at 100o. Alternatively, it has been crystallised from acetone by allowing the solution to evaporate at 37o in an open beaker. It has also been recrystallised from EtOH and dried in a vacuum oven. [Beilstein 19 I 721, 19 II 248, 19 III/IV 2904, 19/8 V 456.]
Properties of FLAVONE
Melting point: | 94-97 °C (lit.) |
Boiling point: | 185 °C / 1mmHg |
Density | 1.1404 (rough estimate) |
refractive index | 1.6600 (estimate) |
storage temp. | Sealed in dry,Room Temperature |
solubility | >38.3 mg/mL in EtOH; >52.3 mg/mL in DMSO |
form | Crystalline Powder |
color | White |
Water Solubility | Soluble in acetone (25 mg/ml), methanol, alcohol, and chloroform. Insoluble in water. |
Merck | 14,4092 |
BRN | 157598 |
CAS DataBase Reference | 525-82-6(CAS DataBase Reference) |
EPA Substance Registry System | Flavone (525-82-6) |
Safety information for FLAVONE
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for FLAVONE
Abamectin manufacturer
PEE ESS AROMATICS
AVIGYABIOSCIENCES PRIVATE LIMITED
Dr. Silviu Pharmachem Pvt., Ltd.
Dr. ASCRO Bio Sciences Private Limited
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