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HomeProduct name listFLAVONE

FLAVONE

Synonym(s):2-Phenyl-4H-1-benzopyran-4-one;2-Phenylchromone

  • CAS NO.:525-82-6
  • Empirical Formula: C15H10O2
  • Molecular Weight: 222.24
  • MDL number: MFCD00006825
  • EINECS: 208-383-8
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-19 23:02:33
FLAVONE Structural

What is FLAVONE?

Chemical properties

white crystalline powder

The Uses of FLAVONE

Flavone is a potentially useful biochemical for cytochrome P450 studies.

What are the applications of Application

Flavone is a potentially useful biochemical for cytochrome P450 studies

Definition

One of a group of flavonoid plant pigments existing as colorless needles, that are insoluble in water and melting at 100C. It fluoresces violet in concentrated sulfuric acid. It can be synthesized. Treatment with alcoholic alkali yields flavanone. The fla

Synthesis Reference(s)

Journal of the American Chemical Society, 79, p. 689, 1957 DOI: 10.1021/ja01560a050
The Journal of Organic Chemistry, 44, p. 497, 1979 DOI: 10.1021/jo01318a005
Tetrahedron Letters, 31, p. 4073, 1990 DOI: 10.1016/S0040-4039(00)94503-9

Metabolism

Not Available

Purification Methods

Dissolve it in dilute aqueous NaOH, filter and precipitate it by adding dilute (1:1) HCl. The process is repeated twice more, and the fluorescein is dried at 100o. Alternatively, it has been crystallised from acetone by allowing the solution to evaporate at 37o in an open beaker. It has also been recrystallised from EtOH and dried in a vacuum oven. [Beilstein 19 I 721, 19 II 248, 19 III/IV 2904, 19/8 V 456.]

Properties of FLAVONE

Melting point: 94-97 °C (lit.)
Boiling point: 185 °C / 1mmHg
Density  1.1404 (rough estimate)
refractive index  1.6600 (estimate)
storage temp.  Sealed in dry,Room Temperature
solubility  >38.3 mg/mL in EtOH; >52.3 mg/mL in DMSO
form  Crystalline Powder
color  White
Water Solubility  Soluble in acetone (25 mg/ml), methanol, alcohol, and chloroform. Insoluble in water.
Merck  14,4092
BRN  157598
CAS DataBase Reference 525-82-6(CAS DataBase Reference)
EPA Substance Registry System Flavone (525-82-6)

Safety information for FLAVONE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for FLAVONE

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