FGIN-1-27
Synonym(s):FGIN-1-27
- CAS NO.：142720-24-9
- Empirical Formula: C28H37FN2O
- Molecular Weight: 436.6
- MDL number: MFCD00467704
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:18
What is FGIN-1-27?
Chemical properties
white to off-white powder
The Uses of FGIN-1-27
FGIN-1-27 is a potent inositol monophosphatase inhibitor.
What are the applications of Application
FGIN-1-27 is a potent inositol monophosphatase inhibitor
Definition
ChEBI: 2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide is a phenylindole.
Biological Activity
Binds specifically and with high affinity to the peptide DBI receptor (benzodiazepine receptor) on mitochondrial membranes, inducing production of neurosteroids, which modulate GABA receptors (EC 50 = 3 nM for increase in production of pregnenolone in glial cells). Thus it reduces anxiety without causing sedation.
storage
Room temperature
Properties of FGIN-1-27
| Melting point: | 96-97 °C |
| Boiling point: | 608.3±55.0 °C(Predicted) |
| Density | 1.0538 (estimate) |
| storage temp. | 2-8°C |
| solubility | methanol: 20 mg/mL |
| form | White powder. |
| pka | 16.45±0.30(Predicted) |
| color | Off-white to light yellow |
Safety information for FGIN-1-27
Computed Descriptors for FGIN-1-27
New Products
6-Bromo 2-Iodo Indole Pyridine 2,4,6-Tricarboxaldehyde Fosfomycin EP impurity D Rimegepant Impurity 3 Ivermectin EP Impurity B Tubulysin F Tubulysin M Tubulysin I Tubulysin C 2,2-diethoxyethanethioamide 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate Fuel shell Imeglimin Hydrochloride IH Calcium Sodium Phosphosilicate IH (S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-((S)-2-oxopyrrolidin-3-yl)propanoate Benzene butanoic acid, 2-hydroxy-3-iodo-, methyl ester Diethyl 2,5-di(furan-2-yl)terephthalate Methyl 4-amino-3-(4-phenylpiperazin-1-yl)benzoate 2-Chloro-3-(chloromethyl)pyridine 3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione 6-bromopyridazin-3-amine (4-(1-Hydroxycyclobutyl)phenyl)boronic acid pinacol esterRelated products of tetrahydrofuran
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