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HomeProduct name listFENPIVERINIUM BROMIDE

FENPIVERINIUM BROMIDE

  • CAS NO.:125-60-0
  • Empirical Formula: C22H29BrN2O
  • Molecular Weight: 417.38
  • MDL number: MFCD00865184
  • EINECS: 204-744-9
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-05-04 15:16:36
FENPIVERINIUM BROMIDE Structural

What is FENPIVERINIUM BROMIDE?

Chemical properties

Crystalline Solid

Originator

Fenpiverinium bromide,R L Fine Chem

The Uses of FENPIVERINIUM BROMIDE

Anticholinergic. Antispasmodic.

What are the applications of Application

Fenpiverinium Bromide is an anti-cholinergic and anti-spasmodic

Manufacturing Process

17.5 g diphenylpiperidine ethyl acetonitrile, prepared from sodium amide and 2-piperidinoethyl chloride (D.B. Patent No. 710,227) was heated to reflux with 35 g KOH, 70 ml ethanol and 2 ml water for 6 hours. On cooling rich white crystals dropped. They was filtered off, washed with water to neutral and dried. Then the product was recrystallized from ethanol. Yield of diphenylpiperidine ethyl acetamide 15 g. MP: 186°-187°C.
10 g diphenylpiperidine ethyl acetamide was mixed with 42 g of 17% solution methyl bromide in benzene and 60 ml isopropanol and heated to reflux on a steam bath for 0.5 hour. The solvent was distilled in vacuum to dryness, dissolved in 100 ml of water and the very muddy solution was through a coal filtered. The clear filtrate was distilled off to dryness. Fenpiverinium bromide was light dissolved in water and had neutral reaction.

Therapeutic Function

Spasmolytic

Properties of FENPIVERINIUM BROMIDE

Melting point: 177.5-178.5?C
storage temp.  Refrigerator
solubility  Methanol (Slightly), Water (Slightly, Heated)
form  Solid
color  White to Off-White

Safety information for FENPIVERINIUM BROMIDE

Computed Descriptors for FENPIVERINIUM BROMIDE

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