Ethyl 3-benzoylacrylate

CAS NO.：17450-56-5
Empirical Formula: C12H12O3
Molecular Weight: 204.22
MDL number: MFCD00011533
EINECS: 621-286-9
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-29 11:48:30

What is Ethyl 3-benzoylacrylate?

Chemical properties

clear yellow liquid

The Uses of Ethyl 3-benzoylacrylate

Ethyl 3-benzoylacrylate is an impurity of Enalapril (E555250), an?antihypertensive and an angiotensin-converting enzyme (ACE) inhibitor.

Synthesis Reference(s)

Tetrahedron Letters, 13, p. 407, 1972 DOI: 10.1016/S0040-4039(01)84337-9

General Description

Ethyl 3-benzoylacrylate (ethyl trans-3-benzoylacrylate) undergoes enantioselective guanidine catalyst promoted Michael addition reaction with dithranol to yield Michael adduct.

Properties of Ethyl 3-benzoylacrylate

Melting point:	32 °C
Boiling point:	184-185 °C/25 mmHg (lit.)
Density	1.112 g/mL at 25 °C (lit.)
refractive index	1.542-1.546
Flash point:	88°C
storage temp.	Sealed in dry,Room Temperature
Specific Gravity	1.112
BRN	2210035
CAS DataBase Reference	17450-56-5(CAS DataBase Reference)

Safety information for Ethyl 3-benzoylacrylate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.