ETHYL 2-FLUOROACETOACETATE
Synonym(s):2-Fluoro-3-oxobutanoic acid ethyl ester;Ethyl 2-fluoro-3-oxobutanoate;Ethyl 2-fluoro-3-oxobutyrate;NSC 24563
- CAS NO.：1522-41-4
- Empirical Formula: C6H9FO3
- Molecular Weight: 148.13
- MDL number: MFCD00215830
- EINECS: 629-671-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 17:06:37
What is ETHYL 2-FLUOROACETOACETATE?
Chemical properties
Clear colorless liquid
The Uses of ETHYL 2-FLUOROACETOACETATE
Reactant for:
- Michael addition-induced cyclization reaction
- Asymmetric Mannich reaction
- Enantioselective organocatalytic conjugate addition
Synthesis Reference(s)
Tetrahedron, 54, p. 2867, 1998 DOI: 10.1016/S0040-4020(98)83023-8
General Description
Ethyl 2-fluoroacetoacetate is an α-fluorinated β-keto ester that can be prepared by the fluorination of ethyl acetoacetate.
Properties of ETHYL 2-FLUOROACETOACETATE
| Boiling point: | 183 °C (lit.) |
| Density | 1.181 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 194 °F |
| form | Liquid |
| pka | 9.25±0.46(Predicted) |
| color | Clear colorless to pale yellow |
| CAS DataBase Reference | 1522-41-4(CAS DataBase Reference) |
Safety information for ETHYL 2-FLUOROACETOACETATE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for ETHYL 2-FLUOROACETOACETATE
| InChIKey | SHTFQLHOTAJQRJ-UHFFFAOYSA-N |
New Products
Tubulysin I Tubulysin C Tubulysin M Tubulysin F Potassium HMDS (1.0 M in THF) Isoxazole, 3-[[[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methyl]thio]-4,5-dihydro-5,5-dimethyl- CYCLOBUTYLAMINE HYDROCHLORIDE 2-(azetidin-3-ylidene)acetonitrile (hydrochloride) 3-N-BOC-(S)-AMINO BUTYRONITRILE 4,4-DIFLUOROCYCLOHEXANAMINE 4-(Benzyloxy)-3-bromophenylacetic Acid 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile Calcium Sodium Phosphosilicate IH 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate Imeglimin Hydrochloride IH 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Fuel shell Lubiprostone Latanoprostene Bunod Magnesium Trisilicate Flame Retardant Zinc Borate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate methyl 3-fluoro-4- thiomorpholino phenylcarbamate 7-Methoxyquinoline-4-carboxylic acidRelated products of tetrahydrofuran
You may like
-
Ethyl 2-Fluoroacetoacetate CAS 1522-41-4View Details
1522-41-4 -
Ethyl 2-fluoroacetoacetate 98% (GC) CAS 1522-41-4View Details
1522-41-4 -
Ethyl 2-fluoroacetoacetate 95% CAS 1522-41-4View Details
1522-41-4 -
(R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonateView Details
2416850-45-6 -
methyl 3-fluoro-4- thiomorpholino phenylcarbamateView Details
2760359-22-4 -
4,6-dichloro-2-propylthiopyrimidine-5-amine 145783-15-9 98%View Details
145783-15-9 -
Valacyclovir Hydrochloride IH 98%View Details
124832-27-5 -
2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 98%View Details
142569-70-8
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.