Esterastin
- CAS NO.：67655-93-0
- Empirical Formula: C28H46N2O6
- Molecular Weight: 506.67
- SAFETY DATA SHEET (SDS)
What is Esterastin?
The Uses of Esterastin
Esterastin is a potent inhibitor of lysosomal acid lipase. Esterastin inhibited the enzyme activity very strongly (IC50, about 80 nM). The inhibition of acid lipase by Esterastin was competitive with respect to the substrate and the inhibition constant for Esterastin was 90 nM. Esterastin was less inhibitory to other lipolytic enzymes, such as pancreatic lipase and carboxylesterase. Thus, Esterastin is a potent new inhibitor of lysosomal acid lipase.
Properties of Esterastin
| storage temp. | Amber Vial, -20°C Freezer, Under inert atmosphere |
Safety information for Esterastin
Computed Descriptors for Esterastin
New Products
Tubulysin A Tubulysin D Tubulysin I 2,2-diethoxyethanethioamide (R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate 2,2-Difluoropropanol 1-(1,1-Difluoroethyl)-2-fluorobenzene 2,2-Difluoropropylamine hydrochloride 4,4-DIFLUOROPIPERIDINE 3-Aminocyclobutanone hydrochloride 4,4-DIFLUOROCYCLOHEXANAMINE 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Imeglimin Hydrochloride IH Calcium Sodium Phosphosilicate IH Fuel shell 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Lubiprostone Latanoprostene Bunod Magnesium Trisilicate Flame Retardant Zinc Borate methyl 3-fluoro-4- thiomorpholino phenylcarbamate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate 1H-Imidazole-4-carbonitrileRelated products of tetrahydrofuran
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