Eritoran
- CAS NO.：185955-34-4
- Empirical Formula: C66H126N2O19P2
- Molecular Weight: 1313.66
- MDL number: MFCD09260033
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:35
What is Eritoran?
Description
Eritoran, a complex molecule with two hexose rings and two phosphate groups, blocks the inflammation pathway mediated by Toll-like receptor (TLR) 4. This mechanism is present in sepsis, but late-stage clinical trials on eritoran failed to show activity against that condition.
Recently, S. N. Vogel and colleagues at the University of Maryland, Baltimore, showed that?eritoran combats flu in rodents. Instead of attacking the flu virus, it treats TLR 4–related inflammation and prevents lung damage.
The Uses of Eritoran
Treatment of sepsis and other diseases due to reaction to bacterial endotoxin (endotoxin antagonist).
Definition
ChEBI: Eritoran is a lipid A derivative used for the treatment of severe sepsis. It is a conjugate acid of an eritoran(4-).
Properties of Eritoran
| Density | 1.14 |
| pka | 1.73±0.10(Predicted) |
| CAS DataBase Reference | 185955-34-4(CAS DataBase Reference) |
Safety information for Eritoran
Computed Descriptors for Eritoran
New Products
(R)-3-Aminobutanenitrile Hydrochloride 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION XANTHAN GUM Racecadotril SODIUM VALPROATE Diclofenac Sodium Methylcobalamin (vitamin B12) SODIUM METHYL PARABEN Folic Acid Impurity G Dabigatran Acyl-O2-D-Glucuronide Trifluoroacetic Acid Salt Glycopyrronium Bromide EP Impurity I Eltrombopag N-Oxide Impurity Di-Nitroso Acyclovir Impurity K DLRD N-OxideRelated products of tetrahydrofuran
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