EPA

CAS NO.：73167-03-0
Empirical Formula: C20H29O2.Na
Molecular Weight: 324.44
MDL number: MFCD00065716
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is EPA?

The Uses of EPA

cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt has been used:

to study its effect on the pathology of lupus in drug-induced and spontaneous mouse models
to pretreat mouse alveolar macrophages to study the effect/relationship between amiodarone and eicosapentaenoic acid (EPA) concerning the cytokine release
to examine if pharmacological correction with EPA supplementation might restore autophagic flux and reduce renal lipotoxicity in mice

The Uses of EPA

reduces thromboxane A2 production and platelet aggregation, inhibits 5-lipoxygenase and prevents arteriosclerosis.

What are the applications of Application

cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt is an inhibitor of 5-LO

General Description

Eicosapentaenoic acid (EPA)/timnodonic acid is an omega-3 polyunsaturated fatty acid (PUFA). This long-chain fatty acid is mainly found in fish oil.

Biochem/physiol Actions

Eicosapentaenoic acid (EPA) possesses anti-hyperglycemic, anti-oxidant, anti-hyperlipidemic, and anti-inflammatory properties. It aids in improving vasoreactivity. EPA is capable of suppressing vascular smooth muscle proliferation. It ameliorates pulmonary hypertension by preventing Fyn kinase activity. EPA exhibits a beneficial effect on lipid metabolism. It is used to treat hypercholesterolemia and atherosclerosis.

Properties of EPA

Melting point:	−54-−53 °C(lit.)
Density	0.943 g/mL at 25 °C(lit.)
refractive index	n20/D 1.4977(lit.)
storage temp.	-20°C
solubility	Ethanol: 1.5 mg/ml; Ethanol:PBS(pH 7.2) (1:5): 0.5 mg/ml
form	waxy solid
color	white