15(S)-HEPE

CAS NO.：86282-92-0
Empirical Formula: C20H30O3
Molecular Weight: 318.45
MDL number: MFCD00065817
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-23 13:36:13

What is 15(S)-HEPE?

Description

15(S)-HEPE is a monohydroxy fatty acid. 15(S)-HEPE is biosynthesized from eicosapentaenoic acid (Item Nos. 90110 | 90110.1 | 21908) by 15-lipoxygenase (15-LO). Serum levels of 15(S)-HEPE are elevated in patients with asthma.

What are the applications of Application

15(S)-HEPE is an eicosapentaenoic acid-derived monohydroxy fatty acid

Definition

ChEBI: 15(S)-HEPE is a 15-HEPE that consists of (5Z,8Z,11Z,13E,17Z)-icosapentaenoic acid in which the 15-hydroxy group has S-configuration. It has a role as a human xenobiotic metabolite. It is a conjugate acid of a 15(S)-HEPE(1-). It is an enantiomer of a 15(R)-HEPE.

Properties of 15(S)-HEPE

Boiling point:	488.0±45.0 °C(Predicted)
Density	0.997±0.06 g/cm3(Predicted)
storage temp.	−20°C
solubility	0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml
pka	4.75±0.10(Predicted)

Safety information for 15(S)-HEPE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.