Entecavir hydrate
Synonym(s):2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one monohydrate
- CAS NO.：209216-23-9
- Empirical Formula: C12H17N5O4
- Molecular Weight: 295.3
- MDL number: MFCD09754448
- EINECS: 606-668-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-05-13 18:00:15
What is Entecavir hydrate?
The Uses of Entecavir hydrate
Entecavir hydrate is an oral antiviral drug used in the treatment of hepatitis B infection. Entecavir hydrate is a nucleoside analog (more specifically, a guanine analogue) that inhibits reverse transcription, DNA replication and transcription in the vira
The Uses of Entecavir hydrate
Entecavir Monohydrate could be a useful compound for treating hepatitis virus B infection.
definition
ChEBI: The monohydrate form of entecavir. A synthetic analogue of 2'-deoxyguanosine, entecavir is a nucleoside reverse transcriptase inhibitor with selective antiviral activity against hepatitis B virus. It is phosphorylated intracellularly to the active triphosp ate form, which competes with deoxyguanosine triphosphate, the natural substrate of hepatitis B virus reverse transcriptase, inhibiting every stage of the enzyme's activity, although it has no activity against HIV. Enteclavir is used for the treatment of c ronic hepatitis B.
brand name
Baraclude (Bristol-Myers Squibb).
Properties of Entecavir hydrate
| Melting point: | >220° |
| alpha | D +35.0° (c = 0.38 in water) |
| Density | 1.81 |
| storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
| solubility | DMSO (Slightly), Methanol (Sparingly), Water (Slightly, Heated, Sonicated) |
| form | Solid |
| color | White to Off-White |
| Merck | 14,3595 |
| CAS DataBase Reference | 209216-23-9(CAS DataBase Reference) |
Safety information for Entecavir hydrate
| Signal word | Danger |
| Pictogram(s) |
 Health Hazard GHS08 |
| GHS Hazard Statements |
H351:Carcinogenicity H372:Specific target organ toxicity, repeated exposure |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P308+P313:IF exposed or concerned: Get medical advice/attention. |
Computed Descriptors for Entecavir hydrate
Abamectin manufacturer
Viruj Pharmaceuticals Pvt Ltd
1Y
Phone:+91-9441591589
Whatsapp: +91 9441591589
product: 209216-23-9 Entecavir Monohydrate USP/IP/PH.Eur 98%
BDR Pharmaceuticals International Pvt Ltd
1Y
Phone:+91-7718884418
Whatsapp: +91-7718884418
product: 209216-23-9 Entecavir monohydrate 98%
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