ENOLASE
Synonym(s):2-Phospho-D -glycerate hydro-lyase;Phosphopyruvate hydratase
- CAS NO.:9014-08-8
- Empirical Formula: NULL
- Molecular Weight: 0
- MDL number: MFCD00131019
- EINECS: 232-754-3
- Update Date: 2023-04-23 13:52:06
What is ENOLASE?
The Uses of ENOLASE
The enzyme from Sigma has been used as an antigen during ELISA. the study used human granulocyte proteins to identify and characterize autoantibodies against catalase and α-enolase in patients with primary sclerosing cholangitis. It has been used to study temperature- and denaturant-induced yeast enolase denaturation using fourier transform infrared spectroscopy. It has also been used along with other proteins to study gradient chromatofocusing-mass spectrometry; a new technique for protein analysis.
Definition
An enzyme active in glycolysis that catalyzes the conversion of 2-phosphoglyceric acid to the phosphorylated enol of pyruvic acid.
General Description
Enolase (2-phosphoglycerate hydratase) is a cytosolic enzyme. This cytosolic metalloenzyme is encoded by three homologous genes in mammals. Enolase the from baker′s yeast is a homodimer containing two bound Mg2+ ions. The peptide consists of 436 amino acids and contains a single cysteine residue and corresponds to a molecular weight of 93 kDa. Two of the active site components include His191 and Arg414. Enolase is seen in archaea, bacteria and eukaryotes.
Biochem/physiol Actions
Enolase plays a key role in glycolysis and gluconeogenesis. Enolase, found in the nucleus of mammalian cells plays a key role in transcriptional modulation of genes, which participates in morphological transformation and cell proliferation.
Properties of ENOLASE
storage temp. | -20°C |
form | lyophilized powder |
CAS DataBase Reference | 9014-08-8 |
EPA Substance Registry System | Hydratase, phosphoenolpyruvate (9014-08-8) |
Safety information for ENOLASE
Computed Descriptors for ENOLASE
New Products
Tubulysin H Tubulysin F Tubulysin G Tubulysin E Tubulysin I Diethyl Aluminium Cyanide (1.0 M in Toluene) CYCLOBUTYLAMINE HYDROCHLORIDE Methyl (R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylate 1-(1,1-Difluoroethyl)-2-fluorobenzene 4,4-DIFLUOROPIPERIDINE 1,2,3,6-TETRAHYDROPYRIDINE HYDROCHLORIDE 2-(azetidin-3-ylidene)acetonitrile (hydrochloride) (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile Fuel shell 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Imeglimin Hydrochloride IH 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate 2,3-dichloro-6- nitrobenzonitrile 2-(2-Formylphenoxy) acetic acid Lubiprostone Magnesium Trisilicate Latanoprostene Bunod Flame Retardant Zinc BorateRelated products of tetrahydrofuran
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