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HomeProduct name listEBELACTONE A

EBELACTONE A

Synonym(s):3,11-Dihydroxy-2,4,6,8,10,12-hexamethyl-9-oxo-6-tetradecenoic acid 1,3-lactone

EBELACTONE A Structural

What is EBELACTONE A?

Description

Ebelactone A is a β-lactone enzyme inhibitor that was first isolated from a cultured strain of soil actinomycetes. It can inhibit esterases, lipases, and N-formylmethionine aminopeptidases (IC50s = 0.056, 0.003, and 0.08 μg/ml, respectively) found on cell surfaces, which has been shown to stimulate host defense in immune cells. Ebelactone A is also reported to inhibit cutinases produced by fungal pathogens, thus demonstrating a plant-protective function.

What are the applications of Application

Ebelactone A is an inhibitor of esterase, formyl methionine aminopeptidase, and acylpeptide hydrolase

Properties of EBELACTONE A

storage temp.  2-8°C
solubility  DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 25 mg/ml; Ethanol: 20 mg/ml
form  White crystalline powder.

Safety information for EBELACTONE A

Computed Descriptors for EBELACTONE A

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