E3 ligase Ligand-Linker Conjugates 4
- CAS NO.：1797406-81-5
- Empirical Formula: C32H47N7O8S
- Molecular Weight: 689.83
- MDL number: MFCD31807302
- Update Date: 2024-07-02 08:55:36
What is E3 ligase Ligand-Linker Conjugates 4?
Description
UUN06815, also known as (S,R,S)-AHPC-PEG4-Azide, is a ProTAC building block. This conjugate contains a von Hippel-Lindau (VHL)-recruiting ligand, a linker with both hydrophobic and hydrophilic moieties, and a pendant azide for click chemistry with an alkyne on the target ligand. When used with other protein degrader building blocks with a pendant azide group, parallel synthesis can be used to more quickly generate ProTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand. This product has no formal name at the moment.
Properties of E3 ligase Ligand-Linker Conjugates 4
| form | Liquid |
| color | Colorless to off-white |
Safety information for E3 ligase Ligand-Linker Conjugates 4
Computed Descriptors for E3 ligase Ligand-Linker Conjugates 4
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