DSPE-PEG-NH2
Synonym(s):1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol)-2000] (ammonium salt)
- CAS NO.：474922-26-4
- Empirical Formula: (C2H4O)nC44H87N2O10P·H3N
- Molecular Weight: 0
- Update Date: 2024-07-02 08:55:03
What is DSPE-PEG-NH2?
Description
DSPE-PEG-Amine, MW 2,000 is a PEG polymer containing DSPE and amine end groups. The DSPE-PEGs have been FDA approved for medical applications. The hydrophobic properties of the DSPE allow for the encapsulation and congregation of other hydrophobic drugs. The hydrophilic PEG increases the water solubility of the overall compound allowing for the delivery of the drug. The amine group can react with activated NHS ester to form a stable amide bond.
Properties of DSPE-PEG-NH2
| storage temp. | Store at -20°C |
| solubility | DMF: 11 mg/ml,Ethanol: 20 mg/ml |
| form | Solid |
| color | White to off-white |
Safety information for DSPE-PEG-NH2
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H331:Acute toxicity,inhalation H336:Specific target organ toxicity,single exposure; Narcotic effects H351:Carcinogenicity H372:Specific target organ toxicity, repeated exposure H412:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P273:Avoid release to the environment. P302+P352:IF ON SKIN: wash with plenty of soap and water. P308+P313:IF exposed or concerned: Get medical advice/attention. |
Computed Descriptors for DSPE-PEG-NH2
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![1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[carboxy(polyethylene glycol)-2000] (aMMoniuM salt)](https://img.chemicalbook.in/)
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