Drinabant
- CAS NO.:358970-97-5
- Empirical Formula: C23H20Cl2F2N2O2S
- Molecular Weight: 497.38
- MDL number: MFCD10567084
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:13
What is Drinabant?
Description
The central cannabinoid (CB1) receptor is a G protein-
The Uses of Drinabant
AVE-1625 is a selective antagonist for the CB1 receptor.
What are the applications of Application
AVE-1625 is a selective antagonist for the CB1 receptor
storage
Store at -20°C
References
[1] borowsky b, stevens r, mark b, et al. ave1625, a cannabinoid cbi antagonist, as a co-treatment for schizophrenia: improvement in cognitive function and reduction of antipsychotic-side effects in animal models[c]//neuropsychopharmacology. macmillan building, 4 crinan st, london n1 9xw, england: nature publishing group, 2005, 30: s116-s117.
[2] herkenham m, lynn a b, little m d, et al. cannabinoid receptor localization in brain[j]. proceedings of the national academy of sciences, 1990, 87(5): 1932-1936.
[3] herling a w, gossel m, haschke g, et al. cb1 receptor antagonist ave1625 affects primarily metabolic parameters independently of reduced food intake in wistar rats[j]. american journal of physiology-endocrinology and metabolism, 2007, 293(3): e826-e832.
Properties of Drinabant
Boiling point: | 581.7±60.0 °C(Predicted) |
Density | 1.458 |
storage temp. | Store at -20°C |
solubility | ≤0.15mg/ml in ethanol;15mg/ml in DMSO;15mg/ml in dimethyl formamide |
form | crystalline solid |
pka | 5.44±0.10(Predicted) |
color | White to off-white |
Safety information for Drinabant
Computed Descriptors for Drinabant
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