COMPUTED DESCRIPTORS
Molecular Weight | 497.4 g/mol |
---|---|
XLogP3 | 5.6 |
Hydrogen Bond Donor Count | 0 |
Hydrogen Bond Acceptor Count | 6 |
Rotatable Bond Count | 6 |
Exact Mass | 496.0590608 g/mol |
Monoisotopic Mass | 496.0590608 g/mol |
Topological Polar Surface Area | 49 Ų |
Heavy Atom Count | 32 |
Formal Charge | 0 |
Complexity | 686 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
AVE-1625 is an oral selective and potent antagonist of cannabinoid 1 (CB1) receptors having the same mechanism of action as rimonabant. It is currently developed in obesity and its associated comorbidities. AVE-1625 is also being developed for the treatment of Alzheimer disease.