Dopexamine hydrochloride
- CAS NO.:86484-91-5
- Empirical Formula: C22H34Cl2N2O2
- Molecular Weight: 429.42356
- MDL number: MFCD00887597
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-09 19:38:33
What is Dopexamine hydrochloride?
Chemical properties
White or almost white, crystalline powder.
The Uses of Dopexamine hydrochloride
Dopexamine is a synthetic dopamine analog and acts as a a β2-adrenergic receptor agonistt as well as an agonist at peripheral dopamine receptors. Dopexamine hydrochloride has been used to improve myocardial and renal performance in patients suffering from low cardiac output states.
The Uses of Dopexamine hydrochloride
Dopexamine is a synthetic dopamine analog and acts as a a β2-adrenergic receptor agonistt as well as an agonist at peripheral dopamine receptors. Dopexamine has been used to improve myocardial and renal performance in patients suffering from low cardiac output states.
brand name
Dopacard (Fisons).
Clinical Use
Inotropic support in exacerbations of heart failure and heart failure associated with cardiac surgery
Drug interactions
Potentially hazardous interactions with other drugs
Anaesthetics: risk of ventricular arrhythmias with
isoflurane - avoid.
Antidepressants: risk of hypertensive crisis with
MAOIs and moclobemide.
Beta-blockers: risk of severe hypertension
Dopaminergics: avoid with rasagiline.
Sympathomimetics: effects of adrennoradrenaline possibly enhanced.
Metabolism
Dopexamine is rapidly eliminated from blood with a halflife of approximately 6-7 minutes in healthy volunteers and around 11 minutes in patients with cardiac failure. Subsequent elimination of the metabolites is by urinary and biliary excretion.
Properties of Dopexamine hydrochloride
Melting point: | 213-215°C |
storage temp. | 2-8°C |
solubility | Soluble in water, sparingly soluble in ethanol (96 per cent) and in methanol, practically insoluble in acetone. |
form | neat |
form | Solid |
color | White to Light Grey |
Stability: | Hygroscopic |
Safety information for Dopexamine hydrochloride
Computed Descriptors for Dopexamine hydrochloride
New Products
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