Dolutegravir Impurity 3
- CAS NO.:1973402-05-9
- Empirical Formula: C20H19F2N3O5
- Molecular Weight: 419.38
- Update Date: 2023-07-14 17:30:25
What is Dolutegravir Impurity 3?
The Uses of Dolutegravir Impurity 3
(R)-N-(2,4-Difluorobenzyl)-9-hydroxy-2-(4-hydroxybutan-2-yl)-1,8-dioxo-2,3,4,8-tetrahydro-1H-pyrido[1,2-a]pyrazine-7-carboxamide is impurity E of Dolutegravir (D528800), which is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.
Properties of Dolutegravir Impurity 3
Melting point: | 95-100°C |
Boiling point: | 662.3±55.0 °C(Predicted) |
Density | 1.51±0.1 g/cm3(Predicted) |
storage temp. | -20°C Freezer, Under inert atmosphere |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | Solid |
pka | 4.50±1.00(Predicted) |
color | Yellow |
Safety information for Dolutegravir Impurity 3
Computed Descriptors for Dolutegravir Impurity 3
Related products of tetrahydrofuran
(4R,12aS)-N-(2,4-Difluorobenzyl)-7-Methoxy-4-Methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-9-carboxaMide
Dolutegravir Impurity 6
GSK1349572 sodiuM salt
GSK1349572
Dolutegravir 2-Desfluoro Impurity
IMpurity of Dolutegravir
Dolutegravir 4-Desfluoro Impurity
Dolutegravir Impurity 5
You may like
-
77-92-9 99%View Details
77-92-9 -
77-92-9 99%View Details
77-92-9 -
8000-27-9 CEDAR WOOD OIL 99%View Details
8000-27-9 -
AMMONIUM DICHROMATE 7789-09-5 99%View Details
7789-09-5 -
7681-57-4 SODIUM METABISULPHITE 99%View Details
7681-57-4 -
77-78-1 DIMETHYL SULPHATE 99%View Details
77-78-1 -
7778-80-5 POTASSIUM SULPHATE 99%View Details
7778-80-5 -
95-54-5 99%View Details
95-54-5
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.